Purpose: to study the Distribution of intraocular pressure in the age group 20-40 years old and the related factors: age, gender, family history, BMI, smoking.
Methods: This was a population-based cross-sectional study of 1000 subjects All particip
ant underwent IOP (intraocular pressure) measurement and a standardized survey for the initial data of the study.
Results: The mean IOP for the study subjects was (17.6mmHg); the mean IOP in men was higher than women (17.53) vs (16.8) mmHg respectively. Ocular hypertension was found in 16.8% participants. IOP increased 0.5 mmHg for every 10 years of age. BMI (Body Mass Index) had a positive association with IOP. Subjects with positive family history of ocular hypertension had higher IOP (18.46) vs (16.98) mmHg. IOP was higher in smokers’ group (17.77) vs (16.29) mmHg. Multivariate analyzing showed that aging, smoking, male sex, family history were independent risk factors for ocular hypertension, otherwise there was no significant relationship between ocular hypertension and BMI.
There is considerable evidence supporting the role of gonadotrophins and
progesterone on follicular growth and maturation and functional maintenance
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plasminogen activator, ornithine decarboxylase, inhibin, activin, follistatin,
relaxine, arginin vasotosin, oxytocin, prostaglandines, vasoactive intestinal
peptide, and their interactions.
