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تسجيل مستخدم جديدA Novel Multi-scale Dilated 3D CNN for Epileptic Seizure Prediction
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Accurate prediction of epileptic seizures allows patients to take preventive measures in advance to avoid possible injuries. In this work, a novel convolutional neural network (CNN) is proposed to analyze time, frequency, and channel information of electroencephalography (EEG) signals. The model uses three-dimensional (3D) kernels to facilitate the feature extraction over the three dimensions. The application of multiscale dilated convolution enables the 3D kernel to have more flexible receptive fields. The proposed CNN model is evaluated with the CHB-MIT EEG database, the experimental results indicate that our model outperforms the existing state-of-the-art, achieves 80.5% accuracy, 85.8% sensitivity and 75.1% specificity.
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Approximately, 50 million people in the world are affected by epilepsy. For patients, the anti-epileptic drugs are not always useful and these drugs may have undesired side effects on a patients health. If the seizure is predicted the patients will h
ave enough time to take preventive measures. The purpose of this work is to investigate the application of bidirectional LSTM for seizure prediction. In this paper, we trained EEG data from canines on a double Bidirectional LSTM layer followed by a fully connected layer. The data was provided in the form of a Kaggle competition by American Epilepsy Society. The main task was to classify the interictal and preictal EEG clips. Using this model, we obtained an AUC of 0.84 on the test dataset. Which shows that our classifiers performance is above chance level on unseen data. The comparison with the previous work shows that the use of bidirectional LSTM networks can achieve significantly better results than SVM and GRU networks.
We propose a computationally efficient algorithm for seizure detection. Instead of using a purely data-driven approach, we develop a hybrid model-based/data-driven method, combining convolutional neural networks with factor graph inference. On the CH
B-MIT dataset, we demonstrate that the proposed method can generalize well in a 6 fold leave-4-patientout evaluation. Moreover, it is shown that our algorithm can achieve as much as 5% absolute improvement in performance compared to previous data-driven methods. This is achieved while the computational complexity of the proposed technique is a fraction of the complexity of prior work, making it suitable for real-time seizure detection.
Objective: Epilepsy is one of the most prevalent neurological diseases among humans and can lead to severe brain injuries, strokes, and brain tumors. Early detection of seizures can help to mitigate injuries, and can be used to aid the treatment of p
atients with epilepsy. The purpose of a seizure prediction system is to successfully identify the pre-ictal brain stage, which occurs before a seizure event. Patient-independent seizure prediction models are designed to offer accurate performance across multiple subjects within a dataset, and have been identified as a real-world solution to the seizure prediction problem. However, little attention has been given for designing such models to adapt to the high inter-subject variability in EEG data. Methods: We propose two patient-independent deep learning architectures with different learning strategies that can learn a global function utilizing data from multiple subjects. Results: Proposed models achieve state-of-the-art performance for seizure prediction on the CHB-MIT-EEG dataset, demonstrating 88.81% and 91.54% accuracy respectively. Conclusions: The Siamese model trained on the proposed learning strategy is able to learn patterns related to patient variations in data while predicting seizures. Significance: Our models show superior performance for patient-independent seizure prediction, and the same architecture can be used as a patient-specific classifier after model adaptation. We are the first study that employs model interpretation to understand classifier behavior for the task for seizure prediction, and we also show that the MFCC feature map utilized by our models contains predictive biomarkers related to interictal and pre-ictal brain states.
An accurate seizure prediction system enables early warnings before seizure onset of epileptic patients. It is extremely important for drug-refractory patients. Conventional seizure prediction works usually rely on features extracted from Electroence
phalography (EEG) recordings and classification algorithms such as regression or support vector machine (SVM) to locate the short time before seizure onset. However, such methods cannot achieve high-accuracy prediction due to information loss of the hand-crafted features and the limited classification ability of regression and SVM algorithms. We propose an end-to-end deep learning solution using a convolutional neural network (CNN) in this paper. One and two dimensional kernels are adopted in the early- and late-stage convolution and max-pooling layers, respectively. The proposed CNN model is evaluated on Kaggle intracranial and CHB-MIT scalp EEG datasets. Overall sensitivity, false prediction rate, and area under receiver operating characteristic curve reaches 93.5%, 0.063/h, 0.981 and 98.8%, 0.074/h, 0.988 on two datasets respectively. Comparison with state-of-the-art works indicates that the proposed model achieves exceeding prediction performance.
Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially catastroph
ic consequences such as injury and death in addition to a long list of potential clinical benefits it may provide for patient care in hospitals. The challenge of seizure forecasting lies within the seemingly unpredictable transitions of brain dynamics into the ictal state. The main body of computational research on determining seizure risk has been focused solely on prediction algorithms, which involves a remarkable issue of balancing accuracy and false-alarms. In this paper, we developed a seizure-risk warning system that employs Bayesian convolutional neural network (BCNN) to provide meaningful information to the patient and provide a greater opportunity for him/her to be potentially more in charge of his/her health. We use scalp electroencephalogram (EEG) signals and release information on the certainty of our automatic seizure-risk assessment. In the process, we pave the ground-work towards incorporating auxiliary signals to improve our EEG-based seizure-risk assessment system. Our previous CNN results show an average AUC of 74.65% while we could achieve on an EEG-only BCNN an average AUC of 68.70%. This drop in performance is the cost of providing richer information to the patient at this stage of this research.
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