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Register a new userCorneal collagen crosslinking in the treatment of bullous keratopathy
تصليب القرنية الضوئي في علاج اعتلال القرنية الفقاعي
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Tishreen University ورقة بحثية
Publication date
2018
fields
Medicine
and research's language is
العربية
Authors
تيم درويش( باحث )
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Shamra Editor
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الهدف: دراسة تأثير تصليب القرنية على اعتلال القرنية الفقاعي المحدث بالعدسات الصنعية الطرق: شارك بالدراسة 15مريض مشخص لديهم اعتلال قرنية فقاعي تالي لاستئصال الساد و زرع عدسات داخل العين. تم إجراء فحص القدرة البصرية المصححة ,الفحص بالمصباح الشقي , تقدير شفافية القرنية و الألم العيني و قياس سماكة القرنية قبل التصليب و بعد شهر, 3 أشهر, 6 أشهر من التصليب. تم اجراء تصليب القرنية بعد إزالة الظهارة و تقطير الريبوفلافين كل 3 دقائق لمدة نصف ساعة ثم تطبيق الاشعة فوق البنفسجية A لمدة نصف ساعة مع تطبيق الريبوفلافين كل 5 دقائق. النتائج: كان العمر الوسطي للمرضى 65.5 سنة (9 اناث و 6 ذكور). حدث تناقص ملحوظ بسماكة القرنية بعد التصليب و لم يكن هناك تغير هام بالقدرة البصرية بعد التصليب. حصل تحسن في شفافية القرنية بالشهر الأول فقط. تناقص الالم العيني بشكل ملحوظ بعد التصليب خاصة بالشهر الأول و الثالث. الاستنتاج: تصليب القرنية الضوئي اجراء فعال و مؤقت لتخفيف الألم العيني لدى مرضى اعتلال القرنية الفقاعي.
Aim: To study the efficacy of collagen crosslinking on pseudophakic bullous keratopathy. Methods: Fifteen patients with pseudophakic bullous keratopathy participated in the study. Corrected visual acuity measurement, slit lamp examination, corneal clarity grading, ocular pain intensity scale and corneal thickness measurement were performed before corneal crosslinking and 1, 3 and 6month postcrosslinking. Corneal collagen crosslinking was performed after the removal of the epithelium and the application of riboflavin every 3 minutes for 30 minutes then the ultraviolet irradiation applied for 30 minutes with the application of riboflavin every 5 minutes. Results: The mean age was 65.5 year (9 females and 6 males). Corneal thickness decreased significantly after crosslinking but the visual acuity did not change significantly after crosslinking. Corneal transparency improved in the first month. Ocular pain decreased significantly in the first and third month. Conclusion: Corneal collagen cross linking is an effective and temporal procedure to decrease ocular pain for bullous keratopathy patients
References used
Goncalves ED, Campos M, Paris F, Gomes JA, Farias CC. Bullous keratopathy: etiopathogenesis and treatment. Arq Bras Oftalmol. 2008;71(6 Suppl):61-64
Gomes JA, Haraguchi DK, Zambrano DU, Izquierdo Junior L, Cunha MC, de Freitas D. Anterior stromal puncture in the treatment of bullous keratopathy: six-month follow-up. Cornea. 2001;20(6):570-2
Uchino Y, Goto E, Takano Y, Dogru M, Shinozaki N, Shimmura S, et al. Long-standing bullous keratopathy is associated with peripheral conjunctivalization and limbal deficiency. Ophthalmology. 2006;113 (7):1098-1101
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سورية
دمشق
الحقل المغنطيسي الأرضي المرجع
المركبة الشمالية
المركبة الشرقية
المركبة الأفقية
المركبة الشاقولية
الانحراف المغنطيسي
الميل المغنطيسي
معاملات توافقية كروية
حلب
دير الزور
(International Geomagnetic Reference Field (IGRF
North component
East component
Horizontal component
Vertical component
Magnetic Declination
Magnetic Inclination
المزيد..
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