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Efficacy Of Botulinum Toxin-A Versus Transcutaneous Electric Nerve Stimulation(Tens) In Treatment of Masticatory System : A Clinical study

دراسة سريرية لتأثير العلاج بالبوتوكس مقارنة مع العلاج بالتنبيه الكهربائي العصبي على العضلات الماضعة

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 Publication date 2016
and research's language is العربية
 Created by Shamra Editor




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The aim of this study was to evaluate the efficacy of botulinum toxin-A (BTX-A) therapy compared with Transcutaneous Electric Nerve Stimulation(TENS) in treatment against temporomandibular disorders clinically study Twenty patients with temporomandibular disorder symptoms and signs were enrolled in the study. The patients were randomly assigned into two groups. Patients in group 1 were injected with 20 IU BTX-A in the masseter and temporal muscle in both sides , whereas patients in group 2 were treated with (TENS),the electrodes were applied on masseter and temporal muscle in both sides, time of stimulation abut 30s ,3perweek for 4 week.


Artificial intelligence review:
Research summary
تهدف هذه الدراسة إلى تقييم فعالية العلاج بالبوتوكس (BTX-A) مقارنة مع العلاج بالتنبيه الكهربائي العصبي عبر الجلد (TENS) في علاج الاضطرابات الفكية الصدغية (TMD). تم تقسيم عشرين مريضًا يعانون من أعراض TMD إلى مجموعتين: مجموعة عولجت بحقن البوتوكس في العضلات الماضغة والصدغية، ومجموعة أخرى عولجت بالـ TENS. تم تقييم مستوى الألم قبل العلاج وبعد شهر وبعد ستة أشهر باستخدام مقياس من 0-3. أظهرت النتائج بعد شهر وجود فروق جوهرية بين الطريقتين لصالح البوتوكس، بينما لم تظهر فروق جوهرية بعد ستة أشهر. خلصت الدراسة إلى أن كلا الطريقتين فعالتين في العلاج العرضي لمدة تصل إلى ستة أشهر، مع تفوق البوتوكس في التأثير العلاجي السريع.
Critical review
دراسة نقدية: تعتبر هذه الدراسة خطوة مهمة في مقارنة فعالية طريقتين شائعتين لعلاج الاضطرابات الفكية الصدغية. ومع ذلك، يمكن توجيه بعض النقد البناء للدراسة. أولاً، حجم العينة صغير نسبيًا (20 مريضًا فقط)، مما قد يؤثر على تعميم النتائج. ثانيًا، لم يتم ذكر تفاصيل حول كيفية اختيار المرضى وتوزيعهم على المجموعتين، مما قد يثير تساؤلات حول العشوائية والتحيز. ثالثًا، لم يتم تناول الآثار الجانبية المحتملة لكل من البوتوكس وTENS بشكل كافٍ، وهو جانب مهم يجب مراعاته عند تقييم فعالية أي علاج. أخيرًا، كان من الأفضل تضمين مجموعة ضابطة لم تتلقَ أي علاج لمقارنة النتائج بشكل أكثر دقة.
Questions related to the research
  1. ما هي الأهداف الرئيسية لهذه الدراسة؟

    تهدف الدراسة إلى تقييم فعالية العلاج بالبوتوكس مقارنة مع العلاج بالتنبيه الكهربائي العصبي عبر الجلد في علاج الاضطرابات الفكية الصدغية.

  2. كم عدد المرضى الذين شاركوا في الدراسة وكيف تم تقسيمهم؟

    شارك في الدراسة عشرون مريضًا تم تقسيمهم إلى مجموعتين: مجموعة عولجت بحقن البوتوكس ومجموعة أخرى عولجت بالـ TENS.

  3. ما هي النتائج الرئيسية التي توصلت إليها الدراسة بعد شهر من العلاج؟

    أظهرت النتائج بعد شهر وجود فروق جوهرية بين الطريقتين لصالح البوتوكس.

  4. هل كانت هناك فروق جوهرية بين الطريقتين بعد ستة أشهر من العلاج؟

    لم تظهر فروق جوهرية بين الطريقتين بعد ستة أشهر من العلاج.


References used
Schwartz , J. Song, C . Blitzer, A 2007 - Oral Diseases ,pages 253–260
OHRBACH, R. STOHLER, CS- 1992- Review of the literature: a current diagnostic system, J CraniomandibDisord , 6: 307–317
Wijer, De. Leeuw, A. Steenks, JR. Bosnian, MH-1996- Temporomandibular and cervical spine disorders: self-reported signs and symptoms, Spine 21: 1638–1646
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