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Register a new userThe ٢nd & ٣rd Lower Molars Development of in utero Gamma Irradiated Mouse Fetus and Neonates
تنامي الضرسين السفليين الثاني و الثالث في أجنة الفأر و الأدراص حديثة الولادة المشععة في الرحم بأشعة غاما
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Damascus University ورقة بحثية
Publication date
2002
fields
Biology
and research's language is
العربية
Authors
محمد عبد القادر عثمان( باحث )
Created by
Shamra Editor
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شععت الأمهات الحوامل بجرعة واحدة من أشعة غاما ( ٦، ٤، ٢، ٠ غري؛ كوبالت ٦٠ )، في الأيام ١٨ ، ١٦، ١٤، ١٢، ١٠ من الحمل، ثم أُخذت رؤوس الأجنة و الأدراص حديثة الولادة، بعد فواصل زمنية متتابعة من التشعيع، بدءًا من اليوم ١٦ من الحمل إلى اليوم الثالث بعد الولادة. و جرى تحري تأثير التشعيع في تنامي الضرسين السفليين الثاني و الثالث، على مقاطع نسيجية متسلسلة، خلال فترات متعاقبة من تكونهما العضوي. و قد أدى التشعيع إلى نقص في نمو الضرسين الثاني و الثالث و تأخير لتناميهما بدرجات مختلفة تبعًا للجرعة و لتوقيت التشعيع و للزمن المنصرم بعد التشعيع.
Pregnant mothers were irradiated by a single dose of gamma rays (٠،٢،٤،٦ Gy, Cobalt ٦٠) in the days ١٠،١٢،١٤،١٦،١٨ of pregnancy. The heads of the embryos’, and those of the neonates were taken at consecutive intervals of irradiation, starting from ١٦ days of pregnancy till ٣rd day after delivery. The effect of irradiation was investigated in the development of the ٢nd and ٣rd lower molars on serial tissue sections, within consecutive periods of their organogenesis. Irradiation led to growth-deficiency in the ٢nd & ٣rd molars, and caused delay in their development. This was observed in various degrees depending on the dose, time of irradiation, and time after irradiation.
References used
Baba T., Terashima T., Oida S., Sasakis. (١٩٩٦)-Determination of enamel protein synthesized by recombined mouse molar tooth germs in organ cultlre. Arch
Baskar R. Devi P. U. (١٩٩٣)-Effect of prenatal Gamma irradiation on the different gestation days on mouse. Bulliten Radiat. Protection
Bernhard E. J., Maity A., Muschel R. J. (١٩٩٥)-Effects of ionizing radiation on cell cycle progression
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Mice embryos were irradiated in utero by gamma rays (٠،٢،٤،٦ Gy) at
١٠،١٢،١٤،١٦،١٨ days of gestation. Histological study was carried out on the
first premandibular molar after ٢،٤،٦،٨ days of irradiation, to investigate the
effect of irradiation on different stages of molar development.
Orange fruits are characterized at harvesting with physical and sensory
properties determine consumer acceptance and in order to identify these
characteristics and vulnerability storage and irradiation conditions, Valancia
orange fruits were subje
cted to gamma irradiation at doses of 0.0, 0.5, 1.0, and
1.5 kGy using gamma 60Co irradiator facility. Fruits were kept in a refrigerator
for 18 weeks. Results indicated that physical and sensory properties of Valencia
orange fruits were affected by storage time and irradiation. The overall color
differences were increased and the firmness of fruits and skin were decreased.
The used doses of gamma irradiation increased the overall color differences of
fruit skin. Whereas the fruit firmness, and the sensory properties (aroma,
color, test and firmness) of irradiated Valencia orange fruits were decreased.
This study involved the irradiation of mouse embryos at different stages of
pregnancy, using dose of ٤ Gy γ-radiation, at ١٠, ١٢, ١٤ and ١٦ days of
pregnancy. Pregnant mice were killed after ٢, ٤ and ٦ days post irradiation.
Embryo’s heads were is
olated and serial cross sections were made to
investigate the effect of irradiation on the different components of the eye at
different periods of eye organogenesis.
It was proved from this study that irradiation causes microphtalmia and
decrease in the growth of lens, retina and corneal stroma, as well severe
disruption in its development and disfigurement in its hitogenesis. These
defects have shown great differences in their severity according to the age of
embryos at exposure and the number of days post irradiation.
Varicose veins affects about 10-59% of the population. Varicose is a clinical reflection of the progressive failure in the veins of the lower limbs. Venous insufficiency is caused by structural imbalances in all layers of the wall of the vein, hence,
the importance of morphologic and statistical studies of the varicose veins of the lower limbs and comparison with normal veins. We had surgery for varicose 43 patients. We examined all samples of varicose veins and normal veins of three patients with pathological studies. Average age was 40.58 years. The study was done macroscopically and microscopically, taking different histological sections of varicose and normal veins. Routine and special Dyes were used, in order to detect changes in the compositional elements of the vein wall. We reached the following conclusions and recommendations: the presence of certain changes in the quality and quantity in all pathologic samples along connective tissue elements and smooth muscle fibers, distributed in all layers of the wall of the vein definitively; the need to start treating varicose veins early as possible in order to avoid its development and access to complications; it is useful to attempt to study the relationship between the appearance of varicose veins and blood group of the patient.
varicose veins particularly the spider veins or reticular and isolated are important medical problem as well as cosmetic harmful for women. there are wide arguments about therapeutic methods for varicose veins. the therapies range from traumatic surg
ical to conservative through laser ablation, and radiofrequency ablation. sclerotherapy may serve as minimally invasive alternatives, we had done therapeutic studying for 35 patients in ALAssaad university hospital in Lattakia between 2014 to april 2015. every patient had been treated by sclerotherapy several sessions, interval between sessions was 2-3 weeks. all patients had been followed up for 6 months after treatment. the treatment had been successfully finished for all patients. but non-dangerous complications had appeared in 54.3% of patients. we had done medical management for them. the sclerotherapy for spider veins or reticular and isolated veins gave excellent results in all patients.
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