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Register a new userThe effects of gabapentin premedication on hemodynamic stability during laparoscopic cholecystectomy
دراسة تأثير التحضير الدوائي بالغابابنتين على الاستقرار الهيموديناميكي أثناء عمليات استئصال المرارة بالتنظير
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أجريت الدراسة في قسم التخدير والإنعاش في مشفيي الأسد و تشرين الجامعيين في عام 2014 - 2015 و شملت 60 مريض من المراجعين لمشفيي الأسد و تشرين الجامعيين باللاذقية من أجل إجراء استئصال المرارة بالتنظير و المصنفينASAƖ , ƖƖ. تم تقسيم المرضى عشوائيا إلى مجموعتين كل مجموعة تضم 30 مريض . - المجموعة الأولى G أعطيت 600 ملغ PO ( فمويا ) من الغابابنتين قبل ساعتين من العمل الجراحي. - المجموعة الثانية P لم تعط أي دواء قبل الجراحة . - تم تناول الغابابنتين قبل ساعتين من مباشرة التخدير . - هدفت الدراسة إلى دراسة تأثير الغابابانتين ( كتحضير دوائي ) على الاستقرار الهيموديناميكي أثناء استئصال المرارة بالتنظير . و بالنتيجة كان هناك استقرار هيموديناميكي واضح لدى المرضى الذين تم تحضيرهم بالغابابنتين قبل العمل الجراحي في كافة نقاط المراقبة . و الخلاصة أن التحضير الدوائي بالغابابنتين يساعد على تأمين الاستقرار الهيموديناميكي أثناء استئصال المرارة بالتنظير .
This study was carried out in the department of anesthesia and reanimation at ALASSAD , TishreenUniversity Hospitals ,Lattakia,Syria,during the year 2014 - 2015,and included 60 patients of either sex (20 – 60 years of age ) under going elective laparoscopic cholecystectomy. Patients were divided into two groups: Patients of group G received oral gabapentin 600 mg 2 hours before inducation of anesthesia , while patients in group p did not receive any drug before the surgery. The goal of the study is studying The effects of gabapentin premedication on hemodynamic stability during laparoscopic cholecystectomy Results : there were significantly hemodynamic stability in patients of group G as compared to group p. Conclusion : Gabapentin premedication provided perioperative hemodynamic stability during laparoscopic cholecystectomy.
References used
BLOBNER M, FELBER AR, GOGLER S. Carbon-dioxide uptake from the pneumoperitoneum during laparoscopicholecystectomy. Anesthesiology. 1992;77:A 37– 40
HODGSON G, MCCLELLAND RM, NEWTON JR. Some effects of the peritoneal insufflation of carbon-dioxide.Anaesthesia. 1970;25:382–9
RICHARDSON JD, TRINKLI EK. Haemodynamic and respiratory alterations with increased intra abdominal pressure. J Surg Res. 1976;20:401–3
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This study included (163) patients admitted to the department of Surgery in Al-Assad
university hospital at Lattakia , between 1/1/2010 and 31/12/2013. They all had
Laparoscopic cholecystectomy due to acute cholecystolithiasis.
The male patients c
omposed (24.5%), and the female patients composed (75.5%) and
the ratio of females to males was (1:3.08).
In our study the age of most patients (53.4 %) was between (21-40) years.
The more frequent clinical features was pain (92.6%) , fever (74.8%) and (nausea +
vomiting) (72.4%).
Ultrasound abdomen was done in (100%).
The most intra – operative complication was perforation of gall bladder and spilled
stones (3.7%) and post – operative complication was spilled bile.
The conversion rate from Laparoscopic cholecystectomy to open method was
(7.4%).
cholecystectomy was done in (50.9%) in the first 72 hours of hospitalization and was
done in (49.1 %) after the 72 hours of hospitalization.
The median operating time was (72) minutes .
The mean stay being (1.7) days.
The aim of the study was to compare the effect of tea and yerba mate on color
stability of two types Nano-filled resin composite materials.
laparoscopic cholecystectomy has many features that make it preferable to open
surgery with a low incidence of complications.
The study was conducted on 877 patients who underwent laparoscopic
cholecystectomy at Al-Assad and Tishreen hospitals in
the period 2010-2017
The surgical method used and the reasons for conversion to open surgery were
studied in addition to the complications occurring during or after the surgery in terms of
occurrence rate and method of management of complications and the results of this
management.
The average age of patients was 46 years, the proportion of females was 64.5%, the
mean surgical time was 45 minutes.
The ratio of conversion to open surgery was 2.05% and the most common cause was
severe inflammation, "unclear calot`s triangle" and suspicion of malignancy.
Partial laparoscopic cholecystectomy was performed in 1.36% of cases and
peroperative complications occurred in 0.34% of cases and postoperative complications in
2.16% of cases.
Analysis of the results revealed that the rates of conversion for open surgery and the
incidence of complications are within the internationally accepted rates and that the results
of management of complications were satisfactory and consistent with the methods used
globally to manage complications.
We concluded that this surgery is safe and its complications are rare. We recommend
applying it in our hospitals . We have suggested some recommendations that can reduce
the complications of this surgery.
Uremic Pruritus is one of the most common and frustrating symptom experience by patients with end-stage renal disease. Approximately 60% of dialysis patients experience pruritis, sometimes worse during the dialysis session.
The aim of this study w
as to determine the effect of gabapentin, 200 mg twice a week (after each hemodialysis session), on uremic pruritus.
Patients older than 18 years who have undergone hemodialysis for more than three months will be enrolled in this double-blind clinical trial.
The patients will be assigned to receive Gabapentin 200 mg following hemodialysis
( twice a week) for a period of four weeks, and after a washout week, they will receive the antihistamines for another four weeks.
The patients will be asked to evaluate the severity of their pruritus using a visual analogue scale (VAS).
Our results assured the efficacy of Gabapentin in the treatment of uremic pruritus, in comparison with Loratadine.
Efforts are being made to connect many wind farms to Syrian electrical network As of Wind turbine the
increases; their Cumulative impact on dynamic operational characteristics of power system will increase.
In this paper, the impact of constant spe
ed wind turbines utilizing squirrel cage induction generators, the
most worldwide spread nowadays, on the transient stability of Syrian power system is analyzed.
Various aspects have been considered like wind turbine penetration level, fault location on power system
overhead lines and network topology transforming.
Results of this study show that wind turbine farms planned to be connected to Syrian electrical network
will have significant impact in improving transient stability parameters (CCT,d).
As the wind turbine penetration level increases, their impact will increase, but still remain dependent on
the fault location and network topology transforming caused by double circuits of overhead lines.
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