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Register a new userMalignant Fibrous Histiocytoma in oral cavity
ورم الخلايا الناسجة الليفي الخبيث في الحفرة الفموية
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Damascus University ورقة بحثية
Publication date
2001
fields
Dentistry
and research's language is
العربية
Created by
Shamra Editor
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على الرغم من أن ورم الخلايا الناسجة الليفي الخبيث قليل المصادفة في الحفرة الفموية فإننا صادفناه في سبع حالات في عظام الفكين ( ٥ في الفك العلوي و ٢ في الفك السفلي ) كلها عند الذكور و تراوحت أعمارهم بين ٢٤-٥١ سنة. ليس لهذا الورم صفات شعاعية مميزة حيث إنَّه يؤدي إلى تخرب عظمي غير واضح الحدود. و كانت أغلب الأنماط النسيجية مشاهدة هو متعدد الأشكال و تميزت جميع الحالات بالخلوية العالية و بأن الخلايا تبدي نشاطا انقساميا جليا و أيضا بغزارة الخلايا الناسجة التي ظهرت باستخدام الملونات المناعية النسيجية الكيميائية 74 CD و 68 CD . و يدخل ضمن التشخيص التفريقي له الورم العفلي العظمي أو الغضروفي أو الليفي و المعالجة المفضلة هي الاستئصال الجراحي الواسع .
Although malignant fibrous histiocytoma are uncommon in the oral cavity. We observed these neoplasms in jawbones in 7 cases (5 in the maxilla and 2 in the mandible) affecting males aged 24 to 51 years. Histologically the pleomorphic pattern is dominant, and all patterns are characterized by active proliferative cells, and scattered histiocytes which stained positively by CD74 and CD68 These lesions cause radiolucencies with poorly defined margins and no radiographically distinct features. Differential diagnosis must involve osteosarcoma, chondrosarcoma and fibrosarcoma . The treatmenm of choice is wide surgical excision.
References used
Asirwatham JE, Pickren JW: Inflammatory fibrous histiocytoma: Case report. Cancer 41: 1467. 1978
Belza MG, Urich H: Chondroma and malignant fibrous histiocytoma: Evidence for transformation . Cancer 58: 1082 – 1087, 1986
Dahlin DC, Unni KK, Matsuno T: Malignant fibrous histiocytoma of bone fact or fancy ? Cancer 39: 1508 – 1516, 1977
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Objective: to study and evaluate the surgical operative process in the management of
Benign Tumors and Leukoplakia in the Oral Cavity by using Laser CO2.
Materials and methods: a total of 18 patients (10 males and 8 females) with mean age
50 years
, and diagnosed with Benign tumorous Lesions or Leukoplakia on mucosa of the
oral cavity, were treated by Vaporization by using CO2 Laser in Al-Assad university
hospital. The postoperative complications were recorded within 7 days after the surgery,
and the wounds was assigned until entire healing.
Results: 8(44%) patients had week pain after 24 hour of surgery, and reduced to
2(11%) patients in the third day. Edema was seen by 8(44%) patients after 24 hour of
surgery, and reduced to 1(6%) patient in the third day.5 (28%) patients showed disturbance
within oral functions, and became 1(6%) patient in the third day. No complications were
seen after 7 days of surgery. No infection or bleeding were recorded within following
time.no statistically significant differences between Lesion kind and pain degree, and no
relationship between Pain degree and Disturbance of the Lesions. Entire healing was
satisfactory in all Wounds and no scar were seen .
Conclusion: CO2 Laser is effective method in manage and minimize the
complications during Healing process after the management of Benign Tumors and
Leukoplakia in oral cavity.
Malignant Pleural Effusion is a common complication of advenced malignancies،
Particularly lung and breast cancer. Many patients experience considerable
dyspnea shortness of breath، dry cough and chest pain، wich decisively reduces
their capacity
for physical activity and their quality of life. Between 1995 – 1998.
39 cases with malignant pleural effusion were treated. Pleurectomy was
performed in 4 cases .The lung was trapped in 5 cases.Pleurodesis with talc slurry
for 25 cases، with Tetracyclin for 4 cases and with Bleomycin for one case were
performed. 73% - of these cases had positive results (decrease the dyspnea، no
effusion) during 1st month .and 66،6% had positive results too during 3 months.
So ،Pleurodesis is an effective and ، simple method of manegement of malignant
Pleural effusion It has also low cost and low complications.
Mitochondria are the major organelles in eukaryotic cells primarily responsible for many cellular functions. Recently, a decrease or increase in mtDNA copy number has been increasingly recognized in human cancers.
cancers (include oral cancers) endanger the human life so they
must be detected, diagnosis early and avoided. More than 90% of these oral
malignancies are squamous cell carcinomas. The prognosis for these
malignancies continues to be poor with approximately 50%survival at five
years.
الموت الخلوي المبرمج
الكينازات مرتبطة بالسيكلين
الجينة Cyclin D
السرطان الفموي
سرطان شائك الخلايا
التلوين بالكيمياء النسيجية المناعية
الجينة السرطانية
programmed cell death
Oral Cancer
Cyclindependent kinase
Squamous cell carcinomas
Oncogenes of Cell Cycle Control
Immunohistochemically
oncogene
المزيد..
Neurofibromas (NFs) are rare neurogenic tumors of the oral cavity. They can present as solitary or multiple when associated with neurofibromatosis-1 (NF-1)/von Recklinghausen's disease. Solitary intraoral NFs unassociated with NF-1 are sporadic and m
imic any other soft tissue tumor of the oral cavity. The authors report a case of a 49-year-old deaf-mute lady who presented with slowly growing solitary mass in the anterolateral aspect of the tongue, which was successfully managed in the outpatient clinic with complete excision and base cauterization under local anesthesia without complicationsز
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