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Register a new userResults of prostate pathology in patients undergoing radical cystectomy
نتائج الفحص الباثولوجي للموثة عند المرضى الخاضعين لاستئصال المثانة الجذري
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Damascus University ورقة بحثية
Publication date
2011
fields
Medicine
and research's language is
العربية
Created by
Shamra Editor
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استئصال المثانة الجذري هو المعالجة المثلى لسرطان المثانة الغازي للعضلية. و بسبب معدل حدوث المضاعفات الجنسية و تلك المتعلقة بالاستمساك البولي عقب استئصال المثانة الجذري فإن طرائق جراحيةً بديلة، مثل استئصال المثانة الجذري مع استئصال جزئي للموثة، قد استخدمت في بعض الحالات بهدف خفض معدل المضاعفات. لتقييم المخاطر الورمية المتعلقة باستئصال المثانة مع المحافظة على جزء من الموثة، و تعرف الموجودات الباثولوجية الموثية عند مرضى استئصال المثانة الجذري بسبب سرطان المثانة الغازي.
Radical cystectomy is the most effective therapeutic approach for patients with muscle-invasive bladder cancer. Due to the incidence of sexual and continence complications associated with this procedure, alternative techniques such as cystectomy with partial prostatectomy have been described in selected cases in order to reduce complications. To evaluate the possible oncological risks of prostate-sparing cystectomy, and to determine the associated pathological findings in the prostate for patients with invasive bladder cancer treated by radical cystoprostatectomy.
References used
Edward M. Messing, Urothelial Tumors of the Bladder, Wein: Campbell-Walsh Urology, 9th ed. 2007 Saunders; section XV; Chapter 75; p2732
Terrone. C, Porpiglia. F, Cracco. C, et al. Supra-ampullar cystectomy and ileal neobladder. Eur Urol 2006; 50; 1223 – 1233
Muto. G, Bardari. F, Giona. C. Seminal sparing cystectomy and ileocapsuloplasty: long-term follow-up results. J Urol 2004; 172; 76 – 80
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The necessity of Meatoplasty In Radical Mastoidectomy for good postoperative
cleaning of mastoid cavity and to reduce recurrence rate.This study aim to evaluate the results of
Meatoplasty By Rotating door flap method In Radical or modified radical
Mastoidectomy (open
technique).
The study is prospective and descriptive it take place in the department of oral surgery in Tishreen university it concerned 32 patients presented a cardiovascular pathology having required an warfarine therapy and also need an act of oral surgery th
e objective of this study was to determine the INR value making possible to carry out an act of oral surgery without haemorrhagic risk we exploited the following parameters: identification of the patient, oral state, type of oral surgery, type of cardiopathy, AVK posology, INR value, means haemostasis.
56.25% of our patients had undergone a single extraction, 25% had beneficed multiple extractions and 18.75% had profited from surgical extraction the average value of the INR was 2.38 with an variance of 0.07 and an ecart type of 0.27. In favour of the haemostat means no haemorrhagic complication post operational was revealed it is allowed that the risk of thromboembolic accident by stoping the treatment is much more prejudicial than hemorrhagic risk for the patent.
Background: low –dose ketoconazole (LDK) in combination with steroids has been
recognized as an effective secondary hormonal therapy in androgen-independent prostate
cancer (AIPC), we hypothesized that low-dose ketoconazole would likewise possess
efficacy and tolerabilitiy in the (AIPC).
Methods: in a single institution (Tishreen University Hospital, Lattakia), patients
with AIPC treated with LDK (at a dose of 200 mg orally 3 times daily ) as secondary
hormonal therapy with concomitant steroids were retrospectively identified, After
experiencing a rising prostate –specific antigen (PSA) level.
Results: 21 of 50 eligible patients)42%) treated with LDK experienced PSA declines
≥ 50% after the start of treatment, while there were 12 patients with low PSA between 25-
50% with a median duration of response (5.4 months) 7 patients less than 25 % decrease,
while 10 patients did not never respond. The most common complications is the fatigue
and general debility in 18 patients , digestive disorders in 21 patients (Summit, nausea and
diarrhea) , muscle disorders in 3 patients, and Metabolic disorders in five patients The
incidence of drug toxicity grade 3-4 is very few. There were only three patients not able to
continue the treatment due to severe side effects.
Conclusion: low dose ketokonazole and Predenisolone is a well – tolerated, relatively
inexpensive and clinically active treatment option. PSA response to low – dose
ketoconazole historically comparable to that of Abiraterone in patients with AIPC.
Uremic Pruritus is one of the most common and frustrating symptom experience by patients with end-stage renal disease. Approximately 60% of dialysis patients experience pruritis, sometimes worse during the dialysis session.
The aim of this study w
as to determine the effect of gabapentin, 200 mg twice a week (after each hemodialysis session), on uremic pruritus.
Patients older than 18 years who have undergone hemodialysis for more than three months will be enrolled in this double-blind clinical trial.
The patients will be assigned to receive Gabapentin 200 mg following hemodialysis
( twice a week) for a period of four weeks, and after a washout week, they will receive the antihistamines for another four weeks.
The patients will be asked to evaluate the severity of their pruritus using a visual analogue scale (VAS).
Our results assured the efficacy of Gabapentin in the treatment of uremic pruritus, in comparison with Loratadine.
Several studies have demonstrated a symptoms of panic disorders and difference
symptoms between men and women .
Study data obtained from 200 patients :100 men and 100 women who met DSM-IVTR
criteria for panic disorder study to diagnosed disorder a
nd treatment it to avoid serious
complications. Common symtoms were :
palpetation, shortness of breath , fear of dying, feeling of dizzy, paraesthias. specific
symptoms occurring with men more than women : shaking and trembling , fear of going
crazy and depersonalization.
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