There are a lot of studies with conflicting results about the correlation between blood
levels of vitamin D and lipid profile (total cholesterol, LDLc, HDLc) and the effect of
treatment with vitamin D supplements on it. This study aimed to investig
ate the effect of
vitamin D and calcium supplements on lipid profile.
This study included 59 volunteers who received these supplements for prevention of
osteoporosis as a prescription from orthopedic doctors between 11/2016 to 1/2018. The
average of age was 49±8 years. The plasma values of TC, LDLc, HDLc were measured
using enzymatic colorimetric method ( Biosystems kits ) in Tishreen hospital before
treatment and after two months. The results were analyzed by T-Student test, and P value
<0.05 was considered significant. The mean plasma levels of LDLc before treatment were
(100.983 ±28.36) mg/dl, and after two months of treatment were (102.249±27.478) mg/dl,
and the difference was not significant. The mean plasma levels of HDLc before treatment
were (68.056 ±14.369) mg/dl and after two months of treatment were (62.715 ± 14.39)
mg/dl, and the difference was significant. We advise to measure plasma lipid levels during
treatment with these supplements depending on the changes that observed in this study.
This study aimed to define the levels of vitamin D3 in postmenopausal women and
their relation with bone mineral density (BMD). The study included 83 women (48-81 year)
who visited the Department of radiology of Al Asad hospital in Lattakia. Bone m
ineral density of
the lumbar spine (L1–L4) and total hip was measured by dual-energy X-ray absorptiometry (DXA).
Blood samples were collected to assay 25(OH)D3 and Ca.
The mean level of 25(OH)D3 was 18.87 ng/ml (6.96 SD) and the prevalence of
vitamin D3 difficiency { 25(OH)D3<20 ng/ml} was 64%. No correlation was found
between BMD and 25(OH)D3 levels [P value>0.05], and no correlation was found between
25(OH)D3 and age or body mass index (IMD). We found a strong correlation between
25(OH)D3 and duration of sun exposure (P value = 0.01). Conclusion: Hypovitaminosis D3
is very common among postmenopausal women. Vitamin D33 status may not be an
important determinant of bone health.
