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This study is aimed to evaluate the role of Platelet Rich Plasma PRP on osteogensis in periosteal distraction. The sample consisted of 12 rabbits from local spices. The sample divided equally into two groups, titanium mesh with holes was used in to elevate the periosteum and the space between the surface of bone and the mesh was filled with collagen sponge, in the test group the sponge was injected with PRP. The rabbits were killed after eight weeks after operation and the samples were prepared for histological study. The histological study of specimens of control group showed formation of small island of osteoid with large areas of connective tissue. While, in test group there was an increasing in bone formation in form of wide area of woven bone and decreasing in connective tissue. We conclude that application of Platelet Rich Plasma PRP lead to improvement in bone formation in periosteal distraction.
The study aimed to Compare the effect of combination Platelet Rich Plasma with bovine derived xenograft and bovine derived xenograft alone in treatment of human class II furcation defects in mandibular molars. Twenty systemically healthy patients, aged 32 to 58 years with chronic periodontitis participated in the study . Each patient had 2 buccal mandibular class II furcation defects (first or second molars) were randomizely treated either with : bovine – derived xenograft with Platelet – Rich plasma, or with bovine - derived xenograft alone.
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