Decreasing serum lipids is still blocked by chemical drugs which have many
side effects, and to achieve a safe medicine, this study aims to investigate the act of aqueous extracts of
dried and fresh Zingiber officinale roscoe at tow doses on the le
vels of total cholesterol, HDL high-density
cholesterol, LDL low-density cholesterol, and TG triglycerides in rat with hypercholesterolemia, resulting
from hypothyroidism, caused by propyltheouracil PTU.
Some local natural sources of antioxidant such as orange peel extract (Citrus
sinensis), pomegranate peel extract (Punica granatum) and ginger extract
(Zingiber officinale L.) were evaluated during 5 days storage of refined palm oil
at 63°C as com
pared to the synthetic antioxidant such as propyl gallate. The
above extracts were obtained with ethanol and oil (palm oil). Those extracts
were added to the oil at two different levels (100 ppm and 200 ppm).
Antioxidant activity of natural extracts, synthetic antioxidant and the control
treatment without antioxidant under thermal treatment (Schaal test) was
assessed by measuring acid value (AV), peroxide value (PV), iodine value (IV)
and refractive index (RI) during 6 days storage of refined palm oil at
temperature mentioned above. Antioxidant activity also measured by studying
the stability of oil by the use of rancimat method. All treatments exhibited
antioxidant activity. Statistical analysis results were shown that the
pomegranate peel extract treatment was significantly (P<0.05) superior than
the orange peel extract and ginger extract treatments whereas, it was not
significant difference about propyl gallate treatment.
The antimicrobial activity of aqueous extract of Zingiber Officinalis
were tested for their antifungal activity against the following
dermatophytes :Candida albicans, Cladosporium cladosporiosis ,
Cryptococcus neuphormans, Trichophyton violaceum a
nd against
other four bacteria : E. coli, Pseudomonas aeruginosa.
Staphylococcus aureus, Streptococcus pyogenes. The extract used in
traditional medicine for the treatment of nausea was tested in vitro
through the Agar Disk Diffusion Method. The minimum inhibitory
concentration (MIC) of extracts determined by the Agar dilution
method ranged from 1.5 to 12.5 mcg. The most sensitive
microorganisms to the extract were Candida albicans with MIC 1.5
and E coli with MIC 1.5 mcg.