دراسة كيميا نسيجية مناعية لدور مستقبل عامل النمو البشروي EGFR في تحديد درجة خبث الإصابة بالسرطان البشروي شائك الخلايا في الحفرة الفموية
Although malignant fibrous histiocytoma are uncommon in the oral
cavity. We observed these neoplasms in jawbones in 7 cases (5 in the
maxilla and 2 in the mandible) affecting males aged 24 to 51 years.
Histologically the pleomorphic pattern is dom
inant, and all patterns are
characterized by active proliferative cells, and scattered histiocytes
which stained positively by CD74 and CD68
These lesions cause radiolucencies with poorly defined margins and no
radiographically distinct features.
Differential diagnosis must involve osteosarcoma, chondrosarcoma and
fibrosarcoma .
The treatmenm of choice is wide surgical excision.
