It is the automatic control engineering knowledge forum, as it
should monitor and control the variables that interact in all
industrial processes to perform functions equipment installations
constructed for her. The automatic control system techno
logy has a
big role in easing the burden of daily life, and make them more
luxury. automatic control applications in most appliances, such as:
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control concepts has been used in various areas of knowledge such
as biology, economics, sociology, medicine and education .
The efficiency of anti-arrhythmic drugs could be weak if they were administrated in insufficient
therapeutic concentrations in target tissues of the cardiac muscle. Anti-arrhythmic drugs concentrations
should be high enough to reach the steady- sta
te for the chronic arrhythmia patients, this could be fatal
due to drug accumulation in the cardiac and body tissues. The most important side effect of all kind of
anti-arrhythmic drugs is the capability to initiate different types of cardiac arrhythmia formations in the
treated individuals. The aim of this study is to prove the effectiveness of delivering an anti-arrhythmic
drug, directly to target tissues of the cardiac muscle by using the Iontophoresis concept, in order to
minimize the side effects in cardiac and body tissues and optimize the benefits of anti-arrhythmic drugs
in target tissues. The results from series of experimental procedures proved that very-low iontophoretic
current's values ranges allow feasible and effective passage of anti-arrhythmic drug's ionized particles
into cardiac tissues, and in the same time they were safe on the innervation of autonomic nervous system
fibers in the cardiac muscle. This study focused on relationships among the different parameters which
control the Iontophoresis procedures.
