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Quantum noise places a fundamental limit on the per photon sensitivity attainable in optical measurements. This limit is of particular importance in biological measurements, where the optical power must be constrained to avoid damage to the specimen. By using non-classically correlated light, we demonstrated that the quantum limit can be surpassed in biological measurements. Quantum enhanced microrheology was performed within yeast cells by tracking naturally occurring lipid granules with sensitivity 2.4 dB beyond the quantum noise limit. The viscoelastic properties of the cytoplasm could thereby be determined with a 64% improved measurement rate. This demonstration paves the way to apply quantum resources broadly in a biological context.
The measurement of a quantum system is often performed by encoding its state in a single observable of a light field. The measurement efficiency of this observable can be reduced by loss or excess noise on the way to the detector. Even a textit{quant
We study an electrostatic qubit monitored by a point-contact detector. Projecting an entire qubit-detector wave function on the detector eigenstates we determine the precision limit for the qubit measurements, allowed by quantum mechanics. We found t
Through simultaneous but unequal electromechanical amplification and cooling processes, we create a method for nearly noiseless pulsed measurement of mechanical motion. We use transient electromechanical amplification (TEA) to monitor a single motion
Magneto-optical sensors including spin noise spectroscopies and magneto-optical Kerr effect microscopies are now ubiquitous tools for materials characterization that can provide new understanding of spin dynamics, hyperfine interactions, spin-orbit i
Under ideal conditions, quantum metrology promises a precision gain over classical techniques scaling quadratically with the number of probe particles. At the same time, no-go results have shown that generic, uncorrelated noise limits the quantum adv