ﻻ يوجد ملخص باللغة العربية
We consider the problem of optimizing expensive black-box functions over discrete spaces (e.g., sets, sequences, graphs). The key challenge is to select a sequence of combinatorial structures to evaluate, in order to identify high-performing structures as quickly as possible. Our main contribution is to introduce and evaluate a new learning-to-search framework for this problem called L2S-DISCO. The key insight is to employ search procedures guided by control knowledge at each step to select the next structure and to improve the control knowledge as new function evaluations are observed. We provide a concrete instantiation of L2S-DISCO for local search procedure and empirically evaluate it on diverse real-world benchmarks. Results show the efficacy of L2S-DISCO over state-of-the-art algorithms in solving complex optimization problems.
Q-learning can be difficult to use in continuous action spaces, because an optimization has to be solved to find the maximal action for the action-values. A common strategy has been to restrict the functional form of the action-values to be concave i
Machine learning has shown potential for optimizing existing molecules with more desirable properties, a critical step towards accelerating new chemical discovery. In this work, we propose QMO, a generic query-based molecule optimization framework th
Robust Policy Search is the problem of learning policies that do not degrade in performance when subject to unseen environment model parameters. It is particularly relevant for transferring policies learned in a simulation environment to the real wor
The promise of machine learning has been explored in a variety of scientific disciplines in the last few years, however, its application on first-principles based computationally expensive tools is still in nascent stage. Even with the advances in co
Predicting clinical outcome is remarkably important but challenging. Research efforts have been paid on seeking significant biomarkers associated with the therapy response or/and patient survival. However, these biomarkers are generally costly and in