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We introduce a new algorithm called {sc Rec-Gen} for reconstructing the genealogy or textit{pedigree} of an extant population purely from its genetic data. We justify our approach by giving a mathematical proof of the effectiveness of {sc Rec-Gen} when applied to pedigrees from an idealized generative model that replicates some of the features of real-world pedigrees. Our algorithm is iterative and provides an accurate reconstruction of a large fraction of the pedigree while having relatively low emph{sample complexity}, measured in terms of the length of the genetic sequences of the population. We propose our approach as a prototype for further investigation of the pedigree reconstruction problem toward the goal of applications to real-world examples. As such, our results have some conceptual bearing on the increasingly important issue of genomic privacy.
A pedigree is a directed graph that describes how individuals are related through ancestry in a sexually-reproducing population. In this paper we explore the question of whether one can reconstruct a pedigree by just observing sequence data for prese
We give the first polynomial-time approximation scheme (PTAS) for the stochastic load balancing problem when the job sizes follow Poisson distributions. This improves upon the 2-approximation algorithm due to Goel and Indyk (FOCS99). Moreover, our ap
We study the problem of estimating the trace of a matrix $A$ that can only be accessed through matrix-vector multiplication. We introduce a new randomized algorithm, Hutch++, which computes a $(1 pm epsilon)$ approximation to $tr(A)$ for any positive
Current bundle adjustment solvers such as the Levenberg-Marquardt (LM) algorithm are limited by the bottleneck in solving the Reduced Camera System (RCS) whose dimension is proportional to the camera number. When the problem is scaled up, this step i
Approximate nearest neighbor algorithms are used to speed up nearest neighbor search in a wide array of applications. However, current indexing methods feature several hyperparameters that need to be tuned to reach an acceptable accuracy--speed trade