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Enhanced responsiveness in asynchronous irregular neuronal networks

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 نشر من قبل Alain Destexhe
 تاريخ النشر 2016
  مجال البحث علم الأحياء
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Networks of excitatory and inhibitory neurons display asynchronous irregular (AI) states, where the activities of the two populations are balanced. At the single cell level, it was shown that neurons subject to balanced and noisy synaptic inputs can display enhanced responsiveness. We show here that this enhanced responsiveness is also present at the network level, but only when single neurons are in a conductance state and fluctuation regime consistent with experimental measurements. In such states, the entire population of neurons is globally influenced by the external input. We suggest that this network-level enhanced responsiveness constitute a low-level form of sensory awareness.



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