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Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being substance m isuse causes poor mental health. However, the lack of evidence on the relationship has resulted in opioids being largely inaccessible through legal means. This study analyzes the substance misuse posts on social media with the opioids being sold through crypto market listings. We use the Drug Abuse Ontology, state-of-the-art deep learning, and BERT-based models to generate sentiment and emotion for the social media posts to understand user perception on social media by investigating questions such as, which synthetic opioids people are optimistic, neutral, or negative about or what kind of drugs induced fear and sorrow or what kind of drugs people love or thankful about or which drug people think negatively about or which opioids cause little to no sentimental reaction. We also perform topic analysis associated with the generated sentiments and emotions to understand which topics correlate with peoples responses to various drugs. Our findings can help shape policy to help isolate opioid use cases where timely intervention may be required to prevent adverse consequences, prevent overdose-related deaths, and worsen the epidemic.
With strong marketing advocacy of the benefits of cannabis use for improved mental health, cannabis legalization is a priority among legislators. However, preliminary scientific research does not conclusively associate cannabis with improved mental h ealth. In this study, we explore the relationship between depression and consumption of cannabis in a targeted social media corpus involving personal use of cannabis with the intent to derive its potential mental health benefit. We use tweets that contain an association among three categories annotated by domain experts - Reason, Effect, and Addiction. The state-of-the-art Natural Langauge Processing techniques fall short in extracting these relationships between cannabis phrases and the depression indicators. We seek to address the limitation by using domain knowledge; specifically, the Drug Abuse Ontology for addiction augmented with Diagnostic and Statistical Manual of Mental Disorders lexicons for mental health. Because of the lack of annotations due to the limited availability of the domain experts time, we use supervised contrastive learning in conjunction with GPT-3 trained on a vast corpus to achieve improved performance even with limited supervision. Experimental results show that our method can significantly extract cannabis-depression relationships better than the state-of-the-art relation extractor. High-quality annotations can be provided using a nearest neighbor approach using the learned representations that can be used by the scientific community to understand the association between cannabis and depression better.
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