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Effect of hypoalbuminemia on the susceptibility of low–density lipoprotein (LDL) to oxidation ; the protective role of antioxidants

تأثير نقص ألبومين الدم في قابلية البروتين الشحمي خفيض الكثافة(LDL) للتأكْسد و الدور الوقائي لمضادات التأكسد

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 Publication date 2003
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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Albumin has an important extra cellular antioxidant effect which prevents lipid peroxidation. This study was conducted to investigate the effect of low albumin level in patients with chronic moderate renal failure(CMRF) and nephritic syndrome(NS) on the susceptibility of LDL to oxidation, and the protective role of vitamins C and A in this process.

References used
(Adachi T , Nakamura M , et al . Quantitative and qualitative changes of extracellular superoxide dismutase in patients with various diseases . Clin. Chim. Acta . , 1994 Sep. ; 229 (1-2
( Decossin C , Tailleux A , Fruchart J . C , et al . Protective of in vitro low – density lipoprotein oxidation by an albumin – containing LpA – 1 subfraction . Bioch. Biophys. Acta. 1995 , Mar 2 ; 1255 ( 1
Demacker P N , Hijmans A G , Vos – Janssen , et al . A study of the use of polyethylene glycol in estimating cholesterol in high – density lipoprotein . Clin. Chem. 1980 ; 26
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