يعد الداء التنكسي من أكثر اضطرابات النسيج الضام مصادفة عند الإنسان،
لذلك هدف معظم الباحثين إلى إيجاد علاج للسيطرة على الألم، و التورم، و إنقاص العجز الناجم عن الفقد التدريجي لوظيفة المفصل و تحسين نمط الحياة و منه استخدم الحمض الهيالوروني الذي يشكل أحد المركبات المهمة للمادة الأساسية للغضروف المفصلي و الطبقات السطحية للغشاء الزليل. حيث يؤدي دوراً رئيساً في الحفاظ على لزوجة هذا السائل و مرونته، و ذلك بالحفاظ على تركيب المادة الأساسية، و تنظيم عمل الخلايا الغضروفية و تنظيم مستقبلات الحمض الهيالوروني-البروتيوغليكان، لذلك عدته الدراسات من الأدوية المعدلة للهيكل الغضروفي.
Osteoarthritis (OA) is a frequent cause of joint pain and is
estimated to be the most common cause of disability in adults. The goals of
management of patients with osteoarthritis (OA) are to control pain and
swelling, minimize disability, improve the quality of life, and educate the
patient about his or her role in the management team. The effects of
intraarticular hyaluronans in OA have been the subject of several studies.
Their aim has been to determine whether intraarticular supplementation of
these macromolecules, which are deficient in degenerative cartilage, can
lead to decreased symptoms of osteoarthritis.
References used
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Kirwan, JR, Elson, CJ. Is the progression of osteoarthritis phasic? Evidence and implications. J Rheumatol 2000; 27:834
Van Dijk GM; Dekker J; Veenhof C; van den Ende CH .Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature. Arthritis Rheum. 2006 Sep 29; 55(5):779-785
The role of arthroscopic debridement in the treatment of osteoarthritis of the knee is
still controversy.
We present in this work a retrospective series including 22 cases of gonarthrosis
treated with arthroscopic debridement of the knee in the Tr
Background: Many options are available for the treatment of synovitis or target joint in hemophilia to prevent recurrent bleeding and further joint destruction when conservative therapy fails such as chemical synovectomy. Chemical synovectomy with Ri
The research provides a comparison between two methods for treating osteoarthritis. In the knee joint using platelet-rich plasma injections after or without arthroscopy, the study included 100 cases every fifty of them were treated in one way and the
This study includes ٨٠ cases of total knee Arthroplasty, They
were treated in Al-Moassat Hospital during the years ٢٠٠٠-
٢٠٠١.
Idiopathic primary osteoarthrihis was the main reason for total
knee Arthroplasly. Some cases of Rheumatoid arthritis w
The rate of venous thromboembolism is unacceptable without prophylaxis.
Venographic studies of patients without prophylaxis show that the deep vein-thrombosis rates range from
40-84% after total knee replacement, and rates of pulmonary embolism ran