شملت الدراسة 84 مصاباً بذات العظم والنقي المزمنة (86 حالة) بأسباب مختلفة، وتوضع ودرجات مختلفة، وقد خضع جميع المرضى لعمل جراحي تمثل بتجريف واستئصال الأنسجة النخرية المنتنة، مع زرع نظام إرواء مستمر بالصادات وتمت متابعة الحالات لمدة سنة،وتم الحصول على نتائج إيجابية في 86% من الحالات، وكانت النتائج سلبية في 14% من الحالات.
استطاعت طريقة الإرواء المستمر بالصادات الحيوية أن تؤمن وصولاً أكيداً للصادات الحيوية المختارة إلى بؤرة الإنتان بالتراكيز الكافية لقتل الجراثيم المسببة، مما سمح بالحصول على أفضل النتائج
Our study included (84) patients: 86 cases suffering from chronic osteomyelitis: various causes, location and degrees.
All patients operated: after curettage of necrotic and infected tissues; system of continuous irrigation with antibiotics was inserted to the infected zone; all cases were followed up for 1 year. 86% of positive results were obtained and results were bad in 14% of cases>
The high positive results (86%) confirm high effect of continuous irrigation with antibiotics as a good method for chronic osteomyelitis treatment, because this method allows delivery of suitable antibiotics in high concentration into the infected area, which is enough to kill microbes and allows to obtain best results.
References used
Abril JC, Castillo F, Loewinsonh AF, Rivas C, Bernacer M. Chronic recurrent multifocal osteomyelitis after cute lymphoblastic leukaemia. Int Orthop 1994;18:126—8
Abril JC, Ramirez A. Successful treatment of chronic recurrent multifocal osteomyelitis with indomethacin: a preliminary report of five cases. J Pediatr Orthop 2007;27:587—91
Anderson SE, Heini P, Sauvain MJ, Geiger L, Johnston JO, Roggo A, et al. Imaging of chronic recurrent multifocal osteomyelitis of childhood first presenting with isolated primary spinal involvement. Skeletal Radiol 2003;32:328—36
Azouz EM, Jurik AG, Bernard C. Sternoclavicular hyperostosis in children: a report of eight cases. AJR 1998;171:461—6
Backmeyer C, Lionnet F, Gibeault M, Damsin JP. Chronic multifocal osteomyelitis due to Clostridium difficile in an adolescent with sickle cell anemia. Pediatr Infect Dis J 2008;27:951—2
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