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Matching Algorithms for Blood Donation

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 Added by Duncan McElfresh
 Publication date 2021
and research's language is English




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Global demand for donated blood far exceeds supply, and unmet need is greatest in low- and middle-income countries; experts suggest that large-scale coordination is necessary to alleviate demand. Using the Facebook Blood Donation tool, we conduct the first large-scale algorithmic matching of blood donors with donation opportunities. While measuring actual donation rates remains a challenge, we measure donor action (e.g., making a donation appointment) as a proxy for actual donation. We develop automated policies for matching donors with donation opportunities, based on an online matching model. We provide theoretical guarantees for these policies, both regarding the number of expected donations and the equitable treatment of blood recipients. In simulations, a simple matching strategy increases the number of donations by 5-10%; a pilot experiment with real donors shows a 5% relative increase in donor action rate (from 3.7% to 3.9%). When scaled to the global Blood Donation tool user base, this corresponds to an increase of around one hundred thousand users taking action toward donation. Further, observing donor action on a social network can shed light onto donor behavior and response to incentives. Our initial findings align with several observations made in the medical and social science literature regarding donor behavior.

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We explore the implications of integrating social distancing with emergency evacuation, as would be expected when a hurricane approaches a city during the COVID-19 pandemic. Specifically, we compare DNN (Deep Neural Network)-based and non-DNN methods for generating evacuation strategies that minimize evacuation time while allowing for social distancing in emergency vehicles. A central question is whether a DNN-based method provides sufficient extra routing efficiency to accommodate increased social distancing in a time-constrained evacuation operation. We describe the problem as a Capacitated Vehicle Routing Problem and solve it using a non-DNN solution (Sweep Algorithm) and a DNN-based solution (Deep Reinforcement Learning). The DNN-based solution can provide decision-makers with more efficient routing than the typical non-DNN routing solution. However, it does not come close to compensating for the extra time required for social distancing, and its advantage disappears as the emergency vehicle capacity approaches the number of people per household.
Eclipse, an open source software project, acknowledges its donors by presenting donation badges in its issue tracking system Bugzilla. However, the rewarding effect of this strategy is currently unknown. We applied a framework of causal inference to investigate relative promptness of developer response to bug reports with donation badges compared with bug reports without the badges, and estimated that donation badges decreases developer response time by a median time of about two hours. The appearance of donation badges is appealing for both donors and organizers because of its practical, rewarding and yet inexpensive effect.
We consider the problem of finding textit{semi-matching} in bipartite graphs which is also extensively studied under various names in the scheduling literature. We give faster algorithms for both weighted and unweighted case. For the weighted case, we give an $O(nmlog n)$-time algorithm, where $n$ is the number of vertices and $m$ is the number of edges, by exploiting the geometric structure of the problem. This improves the classical $O(n^3)$ algorithms by Horn [Operations Research 1973] and Bruno, Coffman and Sethi [Communications of the ACM 1974]. For the unweighted case, the bound could be improved even further. We give a simple divide-and-conquer algorithm which runs in $O(sqrt{n}mlog n)$ time, improving two previous $O(nm)$-time algorithms by Abraham [MSc thesis, University of Glasgow 2003] and Harvey, Ladner, Lovasz and Tamir [WADS 2003 and Journal of Algorithms 2006]. We also extend this algorithm to solve the textit{Balance Edge Cover} problem in $O(sqrt{n}mlog n)$ time, improving the previous $O(nm)$-time algorithm by Harada, Ono, Sadakane and Yamashita [ISAAC 2008].
Let $A$ and $B$ be two point sets in the plane of sizes $r$ and $n$ respectively (assume $r leq n$), and let $k$ be a parameter. A matching between $A$ and $B$ is a family of pairs in $A times B$ so that any point of $A cup B$ appears in at most one pair. Given two positive integers $p$ and $q$, we define the cost of matching $M$ to be $c(M) = sum_{(a, b) in M}|{a-b}|_p^q$ where $|{cdot}|_p$ is the $L_p$-norm. The geometric partial matching problem asks to find the minimum-cost size-$k$ matching between $A$ and $B$. We present efficient algorithms for geometric partial matching problem that work for any powers of $L_p$-norm matching objective: An exact algorithm that runs in $O((n + k^2) {mathop{mathrm{polylog}}} n)$ time, and a $(1 + varepsilon)$-approximation algorithm that runs in $O((n + ksqrt{k}) {mathop{mathrm{polylog}}} n cdot logvarepsilon^{-1})$ time. Both algorithms are based on the primal-dual flow augmentation scheme; the main improvements involve using dynamic data structures to achieve efficient flow augmentations. With similar techniques, we give an exact algorithm for the planar transportation problem running in $O(min{n^2, rn^{3/2}} {mathop{mathrm{polylog}}} n)$ time.
A dominant approach to solving large imperfect-information games is Counterfactural Regret Minimization (CFR). In CFR, many regret minimization problems are combined to solve the game. For very large games, abstraction is typically needed to render CFR tractable. Abstractions are often manually tuned, possibly removing important strategic differences in the full game and harming performance. Function approximation provides a natural solution to finding good abstractions to approximate the full game. A common approach to incorporating function approximation is to learn the inputs needed for a regret minimizing algorithm, allowing for generalization across many regret minimization problems. This paper gives regret bounds when a regret minimizing algorithm uses estimates instead of true values. This form of analysis is the first to generalize to a larger class of $(Phi, f)$-regret matching algorithms, and includes different forms of regret such as swap, internal, and external regret. We demonstrate how these results give a slightly tighter bound for Regression Regret-Matching (RRM), and present a novel bound for combining regression with Hedge.

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