Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userCardiac Functional Analysis with Cine MRI via Deep Learning Reconstruction
127
0
0.0
(
0
)
Ask ChatGPT about the research
No Arabic abstract
Retrospectively gated cine (retro-cine) MRI is the clinical standard for cardiac functional analysis. Deep learning (DL) based methods have been proposed for the reconstruction of highly undersampled MRI data and show superior image quality and magnitude faster reconstruction time than CS-based methods. Nevertheless, it remains unclear whether DL reconstruction is suitable for cardiac function analysis. To address this question, in this study we evaluate and compare the cardiac functional values (EDV, ESV and EF for LV and RV, respectively) obtained from highly accelerated MRI acquisition using DL based reconstruction algorithm (DL-cine) with values from CS-cine and conventional retro-cine. To the best of our knowledge, this is the first work to evaluate the cine MRI with deep learning reconstruction for cardiac function analysis and compare it with other conventional methods. The cardiac functional values obtained from cine MRI with deep learning reconstruction are consistent with values from clinical standard retro-cine MRI.
rate research
Read More
Cine cardiac MRI is routinely acquired for the assessment of cardiac health, but the imaging process is slow and typically requires several breath-holds to acquire sufficient k-space profiles to ensure good image quality. Several undersampling-based reconstruction techniques have been proposed during the last decades to speed up cine cardiac MRI acquisition. However, the undersampling factor is commonly fixed to conservative values before acquisition to ensure diagnostic image quality, potentially leading to unnecessarily long scan times. In this paper, we propose an end-to-end quality-aware cine short-axis cardiac MRI framework that combines image acquisition and reconstruction with downstream tasks such as segmentation, volume curve analysis and estimation of cardiac functional parameters. The goal is to reduce scan time by acquiring only a fraction of k-space data to enable the reconstruction of images that can pass quality control checks and produce reliable estimates of cardiac functional parameters. The framework consists of a deep learning model for the reconstruction of 2D+t cardiac cine MRI images from undersampled data, an image quality-control step to detect good quality reconstructions, followed by a deep learning model for bi-ventricular segmentation, a quality-control step to detect good quality segmentations and automated calculation of cardiac functional parameters. To demonstrate the feasibility of the proposed approach, we perform simulations using a cohort of selected participants from the UK Biobank (n=270), 200 healthy subjects and 70 patients with cardiomyopathies. Our results show that we can produce quality-controlled images in a scan time reduced from 12 to 4 seconds per slice, enabling reliable estimates of cardiac functional parameters such as ejection fraction within 5% mean absolute error.
Assessment of cardiovascular disease (CVD) with cine magnetic resonance imaging (MRI) has been used to non-invasively evaluate detailed cardiac structure and function. Accurate segmentation of cardiac structures from cine MRI is a crucial step for early diagnosis and prognosis of CVD, and has been greatly improved with convolutional neural networks (CNN). There, however, are a number of limitations identified in CNN models, such as limited interpretability and high complexity, thus limiting their use in clinical practice. In this work, to address the limitations, we propose a lightweight and interpretable machine learning model, successive subspace learning with the subspace approximation with adjusted bias (Saab) transform, for accurate and efficient segmentation from cine MRI. Specifically, our segmentation framework is comprised of the following steps: (1) sequential expansion of near-to-far neighborhood at different resolutions; (2) channel-wise subspace approximation using the Saab transform for unsupervised dimension reduction; (3) class-wise entropy guided feature selection for supervised dimension reduction; (4) concatenation of features and pixel-wise classification with gradient boost; and (5) conditional random field for post-processing. Experimental results on the ACDC 2017 segmentation database, showed that our framework performed better than state-of-the-art U-Net models with 200$times$ fewer parameters in delineating the left ventricle, right ventricle, and myocardium, thus showing its potential to be used in clinical practice.
Real-time cardiac magnetic resonance imaging (MRI) plays an increasingly important role in guiding various cardiac interventions. In order to provide better visual assistance, the cine MRI frames need to be segmented on-the-fly to avoid noticeable visual lag. In addition, considering reliability and patient data privacy, the computation is preferably done on local hardware. State-of-the-art MRI segmentation methods mostly focus on accuracy only, and can hardly be adopted for real-time application or on local hardware. In this work, we present the first hardware-aware multi-scale neural architecture search (NAS) framework for real-time 3D cardiac cine MRI segmentation. The proposed framework incorporates a latency regularization term into the loss function to handle real-time constraints, with the consideration of underlying hardware. In addition, the formulation is fully differentiable with respect to the architecture parameters, so that stochastic gradient descent (SGD) can be used for optimization to reduce the computation cost while maintaining optimization quality. Experimental results on ACDC MICCAI 2017 dataset demonstrate that our hardware-aware multi-scale NAS framework can reduce the latency by up to 3.5 times and satisfy the real-time constraints, while still achieving competitive segmentation accuracy, compared with the state-of-the-art NAS segmentation framework.
Deep learning has achieved good success in cardiac magnetic resonance imaging (MRI) reconstruction, in which convolutional neural networks (CNNs) learn a mapping from the undersampled k-space to the fully sampled images. Although these deep learning methods can improve the reconstruction quality compared with iterative methods without requiring complex parameter selection or lengthy reconstruction time, the following issues still need to be addressed: 1) all these methods are based on big data and require a large amount of fully sampled MRI data, which is always difficult to obtain for cardiac MRI; 2) the effect of coil correlation on reconstruction in deep learning methods for dynamic MR imaging has never been studied. In this paper, we propose an unsupervised deep learning method for multi-coil cine MRI via a time-interleaved sampling strategy. Specifically, a time-interleaved acquisition scheme is utilized to build a set of fully encoded reference data by directly merging the k-space data of adjacent time frames. Then these fully encoded data can be used to train a parallel network for reconstructing images of each coil separately. Finally, the images from each coil are combined via a CNN to implicitly explore the correlations between coils. The comparisons with classic k-t FOCUSS, k-t SLR, L+S and KLR methods on in vivo datasets show that our method can achieve improved reconstruction results in an extremely short amount of time.
Many real-world signal sources are complex-valued, having real and imaginary components. However, the vast majority of existing deep learning platforms and network architectures do not support the use of complex-valued data. MRI data is inherently complex-valued, so existing approaches discard the richer algebraic structure of the complex data. In this work, we investigate end-to-end complex-valued convolutional neural networks - specifically, for image reconstruction in lieu of two-channel real-valued networks. We apply this to magnetic resonance imaging reconstruction for the purpose of accelerating scan times and determine the performance of various promising complex-valued activation functions. We find that complex-valued CNNs with complex-valued convolutions provide superior reconstructions compared to real-valued convolutions with the same number of trainable parameters, over a variety of network architectures and datasets.
suggested questions
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
