Early and accurate detection of kidney involvement in primary and secondary glomerulopathy, and therapeutic regimen mayimprove outcomes. Renal biopsy is required for definitive diagnosisof renal disease.
This study investigated whether patients with
proteinuria < 1500 my/24 h without ARF have significant renal disease and should be biopsied. 50 patientsunderwent kidney biopsies during 2011-2013 in Al-Assad University Hospital and Al-Mousah University Hospital in Damascus. Sixteen of them have 24-h urine protein < 1500 mg andnormal kidney function.Female to male ratio was 3:1. Five patients(31.25%) have MN, 3 patients (18.75%) have FSGS, 2 patients (12.5%) have MCD, one case (6.25%) MPGN, and finely 5 patients (31.25%) have LNfrom which there is a case with class I,2 cases with class III(superimposed classV),and a case with IV(superimposed classV), and one case with class V.Out of 8 patients without hematuria at the time of biopsy, 2 (25%) had MN, 2 (25%) had FSGS,one patient(12.5%) MCD, 3 patients(37.5%) had LN.Three patients (18.75%) hadproteinuria <500 mg/24 h, andwere diagnosed with (MN,MCD,MPGN).Our findings showa significant renal involvement(MN-FSGS-MPGN-LN), whichreveals the importanceof conducting biopsyearly and routinely in the patient population.
renal biopsy
proteinuria
(Focal Segmental Glomerulosclerosis (FSGS
(Membranous Nephropathy (MN
(Lupus Nephritis (LN
(Membranoproliferative Glomerulonephritis (MPGN
(Minimal Change Disease (MCD
خزعة الكلية
بيلة بروتينية
تصلب كبي قطعي بؤري
التهاب كبب و كلية غشائي تكاثري
اعتلال كلوي ذئبي
اعتلال كلوي غشائي
الداء قليل التبدلات
المزيد..
Preeclampsia is associated with abnormal lipid metabolism, including fatty acid
metabolism. Carnitine plays an indispensable role in the oxidation of fatty acids. The aim of the study was
to evaluate the possible role of abnormal fatty acid oxidati
on in preeclampsia by comparing plasma
carnitine levels between preeclamptic and healthy control pregnant women.