Clinicians are occasionally faced with the dilemma of
managing pregnant patients who require ongoing anticoagulation.
Examples include women with mechanical heart valves, venous
thromboembolism, and chronic atrial fibrillation.
Methods : A prospe
ctive study randomly assigned 33 pregnant women aged
between 22 and 43 years (average; 28.4); to receive either fractionated
heparin: Enoxaparin (The 1st group, n = 17) or unfractionated heparin (The
second group, n=16).
In both groups, patients were given heparin (fractionated or unfractionated)
during the 1st trimester and last month of pregnancy, and took warfarin
between the 4th and 8th month.
