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To calculate the dose distributions of 6 MeV photon beam at variable depth in 3D water phantom the MCNP4C2 code was used, and the simulated dose profile was compared with that of the treatment planning computer system (TPS), and a good agreement w as found between them. In conclusion, the MCNP4C2 code package presents a good tool adaptable to get dose distributions for the 6MeV photon beam and it can be considered as confirmed method for patient dose calculations.
The aim of this paper is to determine the best optical-probe geometry that would help to detect neoplastic lesions in oral epithelial tissue. Two Geometrical configurations are investigated. The first one implements different distances between the illumination and collection fibers, and the second one implements different fiber diameters. Both of these geometries are evaluated for their collection efficiency and depth resolution. The effect of numerical aperture (NA) and tissue optical properties on the fluorescence signal are also studied. Optical properties of dysplastic tongue epithelial multi-layered tissue were used as an input for Monte Carlo simulation. The results show that the sensitivity to superficial layers can be achieved using small fiber diameters. On the contrary, the sensitivity to deeper layers can be achieved using larger distances between illumination and collection fibers.
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