Alleviating pain in children is one of the most exciting and rewarding of
professional activities . pediatric regional anesthesia is receiving its deserved attention as an excellent
technique for a balanced intraoperative anesthesia as well as post
operative analgesia .
Continuous caudal block provides adequate duration of analgesia, not only for lower limb and lower
abdominal surgeries, but also for upper abdominal and thoracic surgery , conserving the haemodynamic
stability .
We had shown that the mechanism of analgesia induced by swimming
stress in Wistar males is closely related to stress, some of the relation to this
mechanism with cortical hormones. The aims of this research is to study the
sexual differences in th
e mechanism of analgesia induced by swimming stress in
both male and female Wistar rats and the possibility of its relation with sexual
hormones.
The male and female show an increase in the threshold of pain as result of
swimming stress (Swimming in the water during 3 minutes, with 16 C). The
analgesia in the females was more important compared with males. The
pretreatment with naloxone led to a partial inhibition of stress- induced
analgesia in both sexes, but in males it was more important.
The adreno-cortical hormones ,are considered one of the most important
parts of the nonspecific reaction of the organism to different stress effects
including the stress induced analgesia . This paper is interested in the study of
the effect of re
peated cold stress(swimming in cold water ١٧ c for ten minutes)
and the emotional stress (immobilization for ten minutes) for the average of six
times daily for six days,(on the test of tail flick latency) in normal and
adrenalectomized rats . The aim is to know the analgesic system and their
probable relation wth the adreno-cortical hormones .
