Late – Stage Laryngeal Carcinoma (T3-T4 ) Has A High Incidence Of Cervical
Metastasis . The Incidence Of Subclinical Metastasis Is Not Well Described In None Irradiation And
Irradiation Patients Initially Clinically T3,T4) With Negative Nodes Of Th
e Neck ,And The Treatment Of
These Patients Is Contraversal.
Identify The Incidence Of Subclinical Metastatic Disease In (T3,T4) ) With Negative Nodes Of The Neck
Undergoing Functional Neck Dissections With Laryngectomy. And Identify The Incidence Of Subclinical
Metastatic Disease In Those Patients Who Faild Radiotherapy. Are There Any Benefits Of Cts In Those
Patients? .And What Is The Most Aproprait Therapy?.
الهدف من الدراسة: تقييم نتائج العلاج الشعاعي لسرطان الحنجرة شائك الخلايا في مراحله المبكرة T1N0M0,T2N0M0 في مركز العلاج الشعاعي بمستشفى البيروني الجامعي
التصميم: دراسة إحصائية تراجعية .
المكان : قسم أمراض الأذن و الأنف و الحنجرة و جراحة الرأس و الع
نق- وحدة الرأس و العنق - مشفى البيروني الجامعي-جامعة دمشق .
Larynx cancer is the most common cancer of the head and neck with the exception of
the skin and it accounts for 2% of all cancer diagnoses, its genesis is directly associated
with alcohol drinking and smoking, squamous cell carcinoma (SCC) is the m
ost common
histological type (95%) of larynx cancer.
Aim: The purpose of this study was to evaluate 3D conformal radiotherapy of accelerated
system for early larynx cancer and to estimate acute and late toxicity which appear because
of irradiated normal tissues around the tumor (thyroid gland, spine cord, ….) and also to
evaluate the rate of recurrence and survival.
Materials and methods: The study was performed of 44 patients of scc larengeal cancer
stage T1/T2, that underwent RT (2015 – 2017), 84% with glottic cancer, the median age
was 63 years, all patients were treated 3D conformal RT, Total dose between (60-66) Gy,
2Gy/fraction (5 fractions in week).Our analysis was to evaluate the acute and late toxicity
dure and after radiotherapy, and also the rate of recurrence and survival.
Results: The most toxicity was dysphagia (42 PTs) 96%, radiodermitis (30 PTs) 70%, the
least toxicity was tooth damage. No evidence of late toxicity, the rate of recurrence (11
PTs) 25%, metastases occur in (1 PT). (6/ 41 PTs) 16.4% were dead.
Conclusion: Radiotherapy is the important role to control early larynx cancer, and 3DRadiotherapy
is giving a large dose to treat the tumor and save the normal tissues around
the tumor from effect of radiation, therefor absence the late toxicity.
