This study was carried out in the department of anesthesia and reanimation at
ALASSAD , TishreenUniversity Hospitals ,Lattakia,Syria,during the year 2014 - 2015,and
included 60 patients of either sex (20 – 60 years of age ) under going elective lap
aroscopic
cholecystectomy.
Patients were divided into two groups:
Patients of group G received oral gabapentin 600 mg 2 hours before inducation of
anesthesia , while patients in group p did not receive any drug before the surgery.
The goal of the study is studying The effects of gabapentin premedication on
hemodynamic stability during laparoscopic cholecystectomy
Results : there were significantly hemodynamic stability in patients of group G as
compared to group p.
Conclusion : Gabapentin premedication provided perioperative hemodynamic
stability during laparoscopic cholecystectomy.
يعتبر غابابنتين من المواد الدوائية غير الثابتة حيث يتدرك غابابنتين بحلقنة داخل الجزيء ليشكل غابابنتين لاكتام عن طريق هجوم محب للنواة للألكيل أمين على كاربونيل كاربوكسيلات متبوع بنزع الماء
