Reflux Esophagitis was diagnosed in 50 % of Acidic Gastro Esophageal Reflux
Disease cases only.
This study aimed to detect the association between Endoscopic Reflux Esophagitis and acidic
Gastroesophageal Reflux disease.
This study was done to evaluate the effectiveness of premedication with simethicone
or N- acetylcysteine (NAC) on enhancing endoscopic visibility in patient undergoing
Esophagogastroduodenoscopy. This was a Randomized Double –blind Clinical Trial.
The
study included 350 children, ranged in age from 6 months to 15 years. patients were
randomly allocated into three groups to receive one of the following premedications
(: group 1 : Placebo, group 2: N- acetylcysteine, group 3: simehticone) with 10 ml of
water at 20 minutes before Esophagogastroduodenoscopy .It was rated the amount of foam
and air bubbles ,and divided into four degrees from 0 to3 degree, The scores of foam and
air bubbles were compared and the duration of endoscope also compared between the three
groups. The amount of foam/air bubbles was significantly lower in the simeticone group
compared with the placebo and NAC group (p 0,0001) The duration of endoscopy was
shorter in the simeticone group (P 0,0001)
