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I provide a simple estimation for the number of macrophages in a tissue, arising from the hypothesis that they should keep infections below a certain threshold, above which neutrophils are recruited from blood circulation. The estimation reads Nm=a Ncel^{alpha}/Nmax, where a is a numerical coefficient, the exponent {alpha} is near 2/3, and Nmax is the maximal number of pathogens a macrophage may engulf in the time interval, tr, between pathogen replications.
Gene expression data for a set of 12 localizations from The Cancer Genome Atlas are processed in order to evaluate an entropy-like magnitude allowing the characterization of tumors and comparison with the corresponding normal tissues. The comparison
Cells forming various epithelial tissues have a strikingly universal distribution for the number of their edges. It is generally assumed that this topological feature is predefined by the statistics of individual cell divisions in growing tissue but
Self-regulation of living tissue as an example of self-organization phenomena in active fractal systems of biological, ecological, and social nature is under consideration. The characteristic feature of these systems is the absence of any governing c
The growth of several biological tissues is known to be controlled in part by local geometrical features, such as the curvature of the tissue interface. This control leads to changes in tissue shape that in turn can affect the tissues evolution. Unde
Can three-dimensional, microvasculature networks still ensure blood supply if individual links fail? We address this question in the sinusoidal network, a plexus-like microvasculature network, which transports nutrient-rich blood to every hepatocyte