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Recent calculations further supports the premise that large-scale synchronous firings of neurons may affect molecular processes. The context is scalp electroencephalography (EEG) during short-term memory (STM) tasks. The mechanism considered is $mathbf{Pi} = mathbf{p} + q mathbf{A}$ (SI units) coupling, where $mathbf{p}$ is the momenta of free $mathrm{Ca}^{2+}$ waves $q$ the charge of $mathrm{Ca}^{2+}$ in units of the electron charge, and $mathbf{A}$ the magnetic vector potential of current $mathbf{I}$ from neuronal minicolumnar firings considered as wires, giving rise to EEG. Data has processed using multiple graphs to identify sections of data to which spline-Laplacian transformations are applied, to fit the statistical mechanics of neocortical interactions (SMNI) model to EEG data, sensitive to synaptic interactions subject to modification by $mathrm{Ca}^{2+}$ waves.
The dynamic behavior of scalp potentials (EEG) is apparently due to some combination of global and local processes with important top-down and bottom-up interactions across spatial scales. In treating global mechanisms, we stress the importance of my
There are several kinds of non-invasive imaging methods that are used to collect data from the brain, e.g., EEG, MEG, PET, SPECT, fMRI, etc. It is difficult to get resolution of information processing using any one of these methods. Approaches to int
Cascading large-amplitude bursts in neural activity, termed avalanches, are thought to provide insight into the complex spatially distributed interactions in neural systems. In human neuroimaging, for example, avalanches occurring during resting-stat
Previous papers have developed a statistical mechanics of neocortical interactions (SMNI) fit to short-term memory and EEG data. Adaptive Simulated Annealing (ASA) has been developed to perform fits to such nonlinear stochastic systems. An N-dimensio
Cells respond to biophysical and biochemical signals. We developed a composite filament from collagen and silica particles modified to interact with collagen and/or present a laminin epitope (IKVAV) crucial for cell-matrix adhesion and signal transdu