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Differentiation of neural-type cells on multi-scale ordered collagen-silica bionanocomposites

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 نشر من قبل Carole Aime
 تاريخ النشر 2020
  مجال البحث علم الأحياء فيزياء
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Cells respond to biophysical and biochemical signals. We developed a composite filament from collagen and silica particles modified to interact with collagen and/or present a laminin epitope (IKVAV) crucial for cell-matrix adhesion and signal transduction. This combines scaffolding and signaling and shows that local tuning of collagen organization enhances cell differentiation.



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