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Recently, deep learning methods have been proposed for quantitative susceptibility mapping (QSM) data processing: background field removal, field-to-source inversion, and single-step QSM reconstruction. However, the conventional padding mechanism used in convolutional neural networks (CNNs) can introduce spatial artifacts, especially in QSM background field removal and single-step QSM which requires inference from total fields with extreme large values at the edge boundaries of volume of interest. To address this issue, we propose an improved padding technique which utilizes the neighboring valid voxels to estimate the invalid voxels of feature maps at volume boundaries in the neural networks. Studies using simulated and in-vivo data show that the proposed padding greatly improves estimation accuracy and reduces artifacts in the results in the tasks of background field removal, field-to-source inversion, and single-step QSM reconstruction.
Magnetic resonance $T_2^*$ mapping and quantitative susceptibility mapping (QSM) provide direct and precise mappings of tissue contrasts. They are widely used to study iron deposition, hemorrhage and calcification in various clinical applications. In
In contrast to fully connected networks, Convolutional Neural Networks (CNNs) achieve efficiency by learning weights associated with local filters with a finite spatial extent. An implication of this is that a filter may know what it is looking at, b
A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve the quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. In PDI, a deep convolutional neura
Locally Rotation Invariant (LRI) image analysis was shown to be fundamental in many applications and in particular in medical imaging where local structures of tissues occur at arbitrary rotations. LRI constituted the cornerstone of several breakthro
A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. A deep convolutional neural network (C