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A continuous real-time respiratory sound automated analysis system is needed in clinical practice. Previously, we established an open access lung sound database, HF_Lung_V1, and automated lung sound analysis algorithms capable of detecting inhalation, exhalation, continuous adventitious sounds (CASs) and discontinuous adventitious sounds (DASs). In this study, HF-Lung-V1 has been further expanded to HF-Lung-V2 with 1.45 times of increase in audio files. The convolutional neural network (CNN)-bidirectional gated recurrent unit (BiGRU) model was separately trained with training datasets of HF_Lung_V1 (V1_Train) and HF_Lung_V2 (V2_Train), and then were used for the performance comparisons of segment detection and event detection on both test datasets of HF_Lung_V1 (V1_Test) and HF_Lung_V2 (V2_Test). The performance of segment detection was measured by accuracy, predictive positive value (PPV), sensitivity, specificity, F1 score, receiver operating characteristic (ROC) curve and area under the curve (AUC), whereas that of event detection was evaluated with PPV, sensitivity, and F1 score. Results indicate that the model performance trained by V2_Train showed improvement on both V1_Test and V2_Test in inhalation, CASs and DASs, particularly in CASs, as well as on V1_Test in exhalation.
A reliable, remote, and continuous real-time respiratory sound monitor with automated respiratory sound analysis ability is urgently required in many clinical scenarios-such as in monitoring disease progression of coronavirus disease 2019-to replace
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