اشترك بالحزمة الذهبية واحصل على وصول غير محدود شمرا أكاديميا
تسجيل مستخدم جديدNonlinear dynamic analysis of an epidemiological model for COVID-19 including public behavior and government action
115
0
0.0
(
0
)
اسأل ChatGPT حول البحث
ﻻ يوجد ملخص باللغة العربية
This paper is concerned with nonlinear modeling and analysis of the COVID-19 pandemic currently ravaging the planet. There are two objectives: to arrive at an appropriate model that captures the collected data faithfully, and to use that as a basis to explore the nonlinear behavior. We use a nonlinear SEIR (Susceptible, Exposed, Infectious & Removed) transmission model with added behavioral and government policy dynamics. We develop a genetic algorithm technique to identify key model parameters employing COVID19 data from South Korea. Stability, bifurcations and dynamic behavior are analyzed. Parametric analysis reveals conditions for sustained epidemic equilibria to occur. This work points to the value of nonlinear dynamic analysis in pandemic modeling and demonstrates the dramatic influence of social and government behavior on disease dynamics.
قيم البحث
اقرأ أيضاً
An epidemiological model is developed for the spread of COVID-19 in South Africa. A variant of the classical compartmental SEIR model, called the SEIQRDP model, is used. As South Africa is still in the early phases of the global COVID-19 pandemic wit
h the confirmed infectious cases not having peaked, the SEIQRDP model is first parameterized on data for Germany, Italy, and South Korea - countries for which the number of infectious cases are well past their peaks. Good fits are achieved with reasonable predictions of where the number of COVID-19 confirmed cases, deaths, and recovered cases will end up and by when. South African data for the period from 23 March to 8 May 2020 is then used to obtain SEIQRDP model parameters. It is found that the model fits the initial disease progression well, but that the long-term predictive capability of the model is rather poor. The South African SEIQRDP model is subsequently recalculated with the basic reproduction number constrained to reported values. The resulting model fits the data well, and long-term predictions appear to be reasonable. The South African SEIQRDP model predicts that the peak in the number of confirmed infectious individuals will occur at the end of October 2020, and that the total number of deaths will range from about 10,000 to 90,000, with a nominal value of about 22,000. All of these predictions are heavily dependent on the disease control measures in place, and the adherence to these measures. These predictions are further shown to be particularly sensitive to parameters used to determine the basic reproduction number. The future aim is to use a feedback control approach together with the South African SEIQRDP model to determine the epidemiological impact of varying lockdown levels proposed by the South African Government.
Several analytical models have been used in this work to describe the evolution of death cases arising from coronavirus (COVID-19). The Death or `D model is a simplified version of the SIR (susceptible-infected-recovered) model, which assumes no reco
very over time, and allows for the transmission-dynamics equations to be solved analytically. The D-model can be extended to describe various focuses of infection, which may account for the original pandemic (D1), the lockdown (D2) and other effects (Dn). The evolution of the COVID-19 pandemic in several countries (China, Spain, Italy, France, UK, Iran, USA and Germany) shows a similar behavior in concord with the D-model trend, characterized by a rapid increase of death cases followed by a slow decline, which are affected by the earliness and efficiency of the lockdown effect. These results are in agreement with more accurate calculations using the extended SIR model with a parametrized solution and more sophisticated Monte Carlo grid simulations, which predict similar trends and indicate a common evolution of the pandemic with universal parameters.
In this work, we adapt the epidemiological SIR model to study the evolution of the dissemination of COVID-19 in Germany and Brazil (nationally, in the State of Paraiba, and in the City of Campina Grande). We prove the well posedness and the continuou
s dependence of the model dynamics on its parameters. We also propose a simple probabilistic method for the evolution of the active cases that is instrumental for the automatic estimation of parameters of the epidemiological model. We obtained statistical estimates of the active cases based the probabilistic method and on the confirmed cases data. From this estimated time series we obtained a time-dependent contagion rate, which reflects a lower or higher adherence to social distancing by the involved populations. By also analysing the data on daily deaths, we obtained the daily lethality and recovery rates. We then integrate the equations of motion of the model using these time-dependent parameters. We validate our epidemiological model by fitting the official data of confirmed, recovered, death, and active cases due to the pandemic with the theoretical predictions. We obtained very good fits of the data with this method. The automated procedure developed here could be used for basically any population with a minimum of extra work. Finally, we also propose and validate a forecasting method based on Markov chains for the evolution of the epidemiological data for up to two weeks.
We present a simple analytical model to describe the fast increase of deaths produced by the corona virus (COVID-19) infections. The D (deaths) model comes from a simplified version of the SIR (susceptible-infected-recovered) model known as SI model.
It assumes that there is no recovery. In that case the dynamical equations can be solved analytically and the result is extended to describe the D-function that depends on three parameters that we can fit to the data. Results for the data from Spain, Italy and China are presented. The model is validated by comparing with the data of deaths in China, which are well described. This allows to make predictions for the development of the disease in Spain and Italy.
Disease transmission is studied through disciplines like epidemiology, applied mathematics, and statistics. Mathematical simulation models for transmission have implications in solving public and personal health challenges. The SIR model uses a compa
rtmental approach including dynamic and nonlinear behavior of transmission through three factors: susceptible, infected, and removed (recovered and deceased) individuals. Using the Lambert W Function, we propose a framework to study solutions of the SIR model. This demonstrates the applications of COVID-19 transmission data to model the spread of a real-world disease. Different models of disease including the SIR, SIRm and SEIR model are compared with respect to their ability to predict disease spread. Physical distancing impacts and personal protection equipment use will be discussed in relevance to the COVID-19 spread.
سجل دخول لتتمكن من نشر تعليقات
التعليقات
جاري جلب التعليقات
سجل دخول لتتمكن من متابعة معايير البحث التي قمت باختيارها
