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Impact of crowders on the morphology of bacterial chromosomes

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 نشر من قبل Debasish Chaudhuri
 تاريخ النشر 2019
  مجال البحث فيزياء
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Inspired by recent experiments on the effects of cytosolic crowders on the organization of bacterial chromosomes, we consider a feather-boa type model chromosome in the presence of non-additive crowders, encapsulated within a cylindrical cell. We observe spontaneous emergence of complementary helicity of the confined polymer and crowders. This feature is reproduced within a simplified effective model of the chromosome. This latter model further establishes the occurrence of longitudinal and transverse spatial segregation transitions between the chromosome and crowders upon increasing crowder size.



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