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It is now common to process volumetric biomedical images using 3D Convolutional Networks (ConvNets). This can be challenging for the teravoxel and even petavoxel images that are being acquired today by light or electron microscopy. Here we introduce chunkflow, a software framework for distributing ConvNet processing over local and cloud GPUs and CPUs. The image volume is divided into overlapping chunks, each chunk is processed by a ConvNet, and the results are blended together to yield the output image. The frontend submits ConvNet tasks to a cloud queue. The tasks are executed by local and cloud GPUs and CPUs. Thanks to the fault-tolerant architecture of Chunkflow, cost can be greatly reduced by utilizing cheap unstable cloud instances. Chunkflow currently supports PyTorch for GPUs and PZnet for CPUs. To illustrate its usage, a large 3D brain image from serial section electron microscopy was processed by a 3D ConvNet with a U-Net style architecture. Chunkflow provides some chunk operations for general use, and the operations can be composed flexibly in a command line interface.
Deep Neural Networks (DNNs) have achieved im- pressive accuracy in many application domains including im- age classification. Training of DNNs is an extremely compute- intensive process and is solved using variants of the stochastic gradient descent
We present a parallel distributed-memory algorithm for large deformation diffeomorphic registration of volumetric images that produces large isochoric deformations (locally volume preserving). Image registration is a key technology in medical image a
A Hybrid cloud is an integration of resources between private and public clouds. It enables users to horizontally scale their on-premises infrastructure up to public clouds in order to improve performance and cut up-front investment cost. This model
While deep convolutional neural networks (CNN) have been successfully applied for 2D image analysis, it is still challenging to apply them to 3D anisotropic volumes, especially when the within-slice resolution is much higher than the between-slice re
We profile the impact of computation and inter-processor communication on the energy consumption and on the scaling of cortical simulations approaching the real-time regime on distributed computing platforms. Also, the speed and energy consumption of