ترغب بنشر مسار تعليمي؟ اضغط هنا

Neural Image Compression for Gigapixel Histopathology Image Analysis

155   0   0.0 ( 0 )
 نشر من قبل David Tellez
 تاريخ النشر 2018
والبحث باللغة English




اسأل ChatGPT حول البحث

We propose Neural Image Compression (NIC), a two-step method to build convolutional neural networks for gigapixel image analysis solely using weak image-level labels. First, gigapixel images are compressed using a neural network trained in an unsupervised fashion, retaining high-level information while suppressing pixel-level noise. Second, a convolutional neural network (CNN) is trained on these compressed image representations to predict image-level labels, avoiding the need for fine-grained manual annotations. We compared several encoding strategies, namely reconstruction error minimization, contrastive training and adversarial feature learning, and evaluated NIC on a synthetic task and two public histopathology datasets. We found that NIC can exploit visual cues associated with image-level labels successfully, integrating both global and local visual information. Furthermore, we visualized the regions of the input gigapixel images where the CNN attended to, and confirmed that they overlapped with annotations from human experts.

قيم البحث

اقرأ أيضاً

The field of neural image compression has witnessed exciting progress as recently proposed architectures already surpass the established transform coding based approaches. While, so far, research has mainly focused on architecture and model improveme nts, in this work we explore content adaptive optimization. To this end, we introduce an iterative procedure which adapts the latent representation to the specific content we wish to compress while keeping the parameters of the network and the predictive model fixed. Our experiments show that this allows for an overall increase in rate-distortion performance, independently of the specific architecture used. Furthermore, we also evaluate this strategy in the context of adapting a pretrained network to other content that is different in visual appearance or resolution. Here, our experiments show that our adaptation strategy can largely close the gap as compared to models specifically trained for the given content while having the benefit that no additional data in the form of model parameter updates has to be transmitted.
Over the past several years, we have witnessed impressive progress in the field of learned image compression. Recent learned image codecs are commonly based on autoencoders, that first encode an image into low-dimensional latent representations and t hen decode them for reconstruction purposes. To capture spatial dependencies in the latent space, prior works exploit hyperprior and spatial context model to build an entropy model, which estimates the bit-rate for end-to-end rate-distortion optimization. However, such an entropy model is suboptimal from two aspects: (1) It fails to capture spatially global correlations among the latents. (2) Cross-channel relationships of the latents are still underexplored. In this paper, we propose the concept of separate entropy coding to leverage a serial decoding process for causal contextual entropy prediction in the latent space. A causal context model is proposed that separates the latents across channels and makes use of cross-channel relationships to generate highly informative contexts. Furthermore, we propose a causal global prediction model, which is able to find global reference points for accurate predictions of unknown points. Both these two models facilitate entropy estimation without the transmission of overhead. In addition, we further adopt a new separate attention module to build more powerful transform networks. Experimental results demonstrate that our full image compression model outperforms standard VVC/H.266 codec on Kodak dataset in terms of both PSNR and MS-SSIM, yielding the state-of-the-art rate-distortion performance.
73 - Xiao Wang , Wei Jiang , Wei Wang 2021
We describe Substitutional Neural Image Compression (SNIC), a general approach for enhancing any neural image compression model, that requires no data or additional tuning of the trained model. It boosts compression performance toward a flexible dist ortion metric and enables bit-rate control using a single model instance. The key idea is to replace the image to be compressed with a substitutional one that outperforms the original one in a desired way. Finding such a substitute is inherently difficult for conventional codecs, yet surprisingly favorable for neural compression models thanks to their fully differentiable structures. With gradients of a particular loss backpropogated to the input, a desired substitute can be efficiently crafted iteratively. We demonstrate the effectiveness of SNIC, when combined with various neural compression models and target metrics, in improving compression quality and performing bit-rate control measured by rate-distortion curves. Empirical results of control precision and generation speed are also discussed.
129 - Thierry Dumas 2018
This paper describes a set of neural network architectures, called Prediction Neural Networks Set (PNNS), based on both fully-connected and convolutional neural networks, for intra image prediction. The choice of neural network for predicting a given image block depends on the block size, hence does not need to be signalled to the decoder. It is shown that, while fully-connected neural networks give good performance for small block sizes, convolutional neural networks provide better predictions in large blocks with complex textures. Thanks to the use of masks of random sizes during training, the neural networks of PNNS well adapt to the available context that may vary, depending on the position of the image block to be predicted. When integrating PNNS into a H.265 codec, PSNR-rate performance gains going from 1.46% to 5.20% are obtained. These gains are on average 0.99% larger than those of prior neural network based methods. Unlike the H.265 intra prediction modes, which are each specialized in predicting a specific texture, the proposed PNNS can model a large set of complex textures.
Hematoxylin and Eosin stained histopathology image analysis is essential for the diagnosis and study of complicated diseases such as cancer. Existing state-of-the-art approaches demand extensive amount of supervised training data from trained patholo gists. In this work we synthesize in an unsupervised manner, large histopathology image datasets, suitable for supervised training tasks. We propose a unified pipeline that: a) generates a set of initial synthetic histopathology images with paired information about the nuclei such as segmentation masks; b) refines the initial synthetic images through a Generative Adversarial Network (GAN) to reference styles; c) trains a task-specific CNN and boosts the performance of the task-specific CNN with on-the-fly generated adversarial examples. Our main contribution is that the synthetic images are not only realistic, but also representative (in reference styles) and relatively challenging for training task-specific CNNs. We test our method for nucleus segmentation using images from four cancer types. When no supervised data exists for a cancer type, our method without supervision cost significantly outperforms supervised methods which perform across-cancer generalization. Even when supervised data exists for all cancer types, our approach without supervision cost performs better than supervised methods.
التعليقات
جاري جلب التعليقات جاري جلب التعليقات
سجل دخول لتتمكن من متابعة معايير البحث التي قمت باختيارها
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا