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In carbon-therapy, the interaction of the incoming beam with human tissues may lead to the production of a large amount of nuclear fragments and secondary light particles. An accurate estimation of the biological dose deposited into the tumor and the surrounding healthy tissues thus requires sophisticated simulation tools based on nuclear reaction models. The validity of such models requires intensive comparisons with as many sets of experimental data as possible. Up to now, a rather limited set of double di erential carbon fragmentation cross sections have been measured in the energy range used in hadrontherapy (up to 400 MeV/A). However, new data have been recently obtained at intermediate energy (95 MeV/A). The aim of this work is to compare the reaction models embedded in the GEANT4 Monte Carlo toolkit with these new data. The strengths and weaknesses of each tested model, i.e. G4BinaryLightIonReaction, G4QMDReaction and INCL++, coupled to two di fferent de-excitation models, i.e. the generalized evaporation model and the Fermi break-up are discussed.
Monte Carlo simulations have been performed in order to evaluate the efficiencies of several light ions identification techniques. The detection system was composed with layers of scintillating material to measure either the deposited energy or the t
During therapeutic treatment with heavy ions like carbon, the beam undergoes nuclear fragmentation and secondary light charged particles, in particular protons and alpha particles, are produced. To estimate the dose deposited into the tumors and the
During therapeutic treatments using ions such as carbon, nuclear interactions between the incident ions and nuclei present in organic tissues may occur, leading to the attenuation of the incident beam intensity and to the production of secondary ligh
We report the design and test results of a beam monitor developed for online monitoring in hadron therapy. The beam monitor uses eight silicon pixel sensors, textit{Topmetal-${II}^-$}, as the anode array. textit{Topmetal-${II}^-$} is a charge sensor
Data on the reaction $gamma pto K^+Lambda$ from the CLAS experiments are used to derive the leading multipoles, $E_{0+}$, $M_{1-}$, $E_{1+}$, and $M_{1+}$, from the production threshold to 2180,MeV in 24 slices of the invariant mass. The four multipo