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تسجيل مستخدم جديدInteraction Models and Generalized Score Matching for Compositional Data
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Applications such as the analysis of microbiome data have led to renewed interest in statistical methods for compositional data, i.e., multivariate data in the form of probability vectors that contain relative proportions. In particular, there is considerable interest in modeling interactions among such relative proportions. To this end we propose a class of exponential family models that accommodate general patterns of pairwise interaction while being supported on the probability simplex. Special cases include the family of Dirichlet distributions as well as Aitchisons additive logistic normal distributions. Generally, the distributions we consider have a density that features a difficult to compute normalizing constant. To circumvent this issue, we design effective estimation methods based on generaliz
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putationally intensive. The score matching method of Hyvarinen [2005] avoids direct calculation of the normalizing constant and yields closed-form estimates for exponential families of continuous distributions over $mathbb{R}^m$. Hyvarinen [2007] extended the approach to distributions supported on the non-negative orthant, $mathbb{R}_+^m$. In this paper, we give a generalized form of score matching for non-negative data that improves estimation efficiency. As an example, we consider a general class of pairwise interaction models. Addressing an overlooked inexistence problem, we generalize the regularized score matching method of Lin et al. [2016] and improve its theoretical guarantees for non-negative Gaussian graphical models.
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