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The Coronavirus disease 2019 (COVID-19) has rapidly spread all over the world since its first report in December 2019 and thoracic computed tomography (CT) has become one of the main tools for its diagnosis. In recent years, deep learning-based approaches have shown impressive performance in myriad image recognition tasks. However, they usually require a large number of annotated data for training. Inspired by Ground Glass Opacity (GGO), a common finding in COIVD-19 patients CT scans, we proposed in this paper a novel self-supervised pretraining method based on pseudo lesions generation and restoration for COVID-19 diagnosis. We used Perlin noise, a gradient noise based mathematical model, to generate lesion-like patterns, which were then randomly pasted to the lung regions of normal CT images to generate pseudo COVID-19 images. The pairs of normal and pseudo COVID-19 images were then used to train an encoder-decoder architecture based U-Net for image restoration, which does not require any labelled data. The pretrained encoder was then fine-tuned using labelled data for COVID-19 diagnosis task. Two public COVID-19 diagnosis datasets made up of CT images were employed for evaluation. Comprehensive experimental results demonstrated that the proposed self-supervised learning approach could extract better feature representation for COVID-19 diagnosis and the accuracy of the proposed method outperformed the supervised model pretrained on large scale images by 6.57% and 3.03% on SARS-CoV-2 dataset and Jinan COVID-19 dataset, respectively.
Segmentation of infected areas in chest CT volumes is of great significance for further diagnosis and treatment of COVID-19 patients. Due to the complex shapes and varied appearances of lesions, a large number of voxel-level labeled samples are gener
Our motivating application is a real-world problem: COVID-19 classification from CT imaging, for which we present an explainable Deep Learning approach based on a semi-supervised classification pipeline that employs variational autoencoders to extrac
The novel coronavirus disease 2019 (COVID-19) characterized by atypical pneumonia has caused millions of deaths worldwide. Automatically segmenting lesions from chest Computed Tomography (CT) is a promising way to assist doctors in COVID-19 screening
How to fast and accurately assess the severity level of COVID-19 is an essential problem, when millions of people are suffering from the pandemic around the world. Currently, the chest CT is regarded as a popular and informative imaging tool for COVI
Radiological image is currently adopted as the visual evidence for COVID-19 diagnosis in clinical. Using deep models to realize automated infection measurement and COVID-19 diagnosis is important for faster examination based on radiological imaging.