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One of the key limitations in conventional deep learning based image reconstruction is the need for registered pairs of training images containing a set of high-quality groundtruth images. This paper addresses this limitation by proposing a novel unsupervised deep registration-augmented reconstruction method (U-Dream) for training deep neural nets to reconstruct high-quality images by directly mapping pairs of unregistered and artifact-corrupted images. The ability of U-Dream to circumvent the need for accurately registered data makes it widely applicable to many biomedical image reconstruction tasks. We validate it in accelerated magnetic resonance imaging (MRI) by training an image reconstruction model directly on pairs of undersampled measurements from images that have undergone nonrigid deformations.
Deep neural networks for medical image reconstruction are traditionally trained using high-quality ground-truth images as training targets. Recent work onNoise2Noise (N2N) has shown the potential of using multiple noisy measurements of the same objec
Regularization by denoising (RED) is an image reconstruction framework that uses an image denoiser as a prior. Recent work has shown the state-of-the-art performance of RED with learned denoisers corresponding to pre-trained convolutional neural nets
We propose a novel deep neural network architecture by mapping the robust proximal gradient scheme for fast image reconstruction in parallel MRI (pMRI) with regularization function trained from data. The proposed network learns to adaptively combine
Recently, deep learning approaches have become the main research frontier for biological image reconstruction problems thanks to their high performance, along with their ultra-fast reconstruction times. However, due to the difficulty of obtaining mat
Direct reconstruction methods have been developed to estimate parametric images directly from the measured PET sinograms by combining the PET imaging model and tracer kinetics in an integrated framework. Due to limited counts received, signal-to-nois