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Regularization by denoising (RED) is an image reconstruction framework that uses an image denoiser as a prior. Recent work has shown the state-of-the-art performance of RED with learned denoisers corresponding to pre-trained convolutional neural nets (CNNs). In this work, we propose to broaden the current denoiser-centric view of RED by considering priors corresponding to networks trained for more general artifact-removal. The key benefit of the proposed family of algorithms, called regularization by artifact-removal (RARE), is that it can leverage priors learned on datasets containing only undersampled measurements. This makes RARE applicable to problems where it is practically impossible to have fully-sampled groundtruth data for training. We validate RARE on both simulated and experimentally collected data by reconstructing a free-breathing whole-body 3D MRIs into ten respiratory phases from heavily undersampled k-space measurements. Our results corroborate the potential of learning regularizers for iterative inversion directly on undersampled and noisy measurements.
Deep neural networks for medical image reconstruction are traditionally trained using high-quality ground-truth images as training targets. Recent work onNoise2Noise (N2N) has shown the potential of using multiple noisy measurements of the same objec
One of the key limitations in conventional deep learning based image reconstruction is the need for registered pairs of training images containing a set of high-quality groundtruth images. This paper addresses this limitation by proposing a novel uns
High-quality magnetic resonance (MR) image, i.e., with near isotropic voxel spacing, is desirable in various scenarios of medical image analysis. However, many MR acquisitions use large inter-slice spacing in clinical practice. In this work, we propo
Deep neural networks have been very successful in image estimation applications such as compressive-sensing and image restoration, as a means to estimate images from partial, blurry, or otherwise degraded measurements. These networks are trained on a
Image denoising is the process of removing noise from noisy images, which is an image domain transferring task, i.e., from a single or several noise level domains to a photo-realistic domain. In this paper, we propose an effective image denoising met