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Single DNA Electron Spin Resonance Spectroscopy in Aqueous Solutions

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 نشر من قبل Fazhan Shi
 تاريخ النشر 2020
  مجال البحث فيزياء
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Magnetic resonance spectroscopy of single biomolecules under near-physiological conditions may substantially advance understanding of biological function, yet remains very challenging. Here we use nitrogen-vacancy centers in diamonds to detect electron spin resonance spectra of individual, tethered DNA duplexes labeled with a nitroxide spin label in aqueous buffer solutions at ambient temperatures. This paves the way for magnetic resonance studies on single biomolecules and their inter-molecular interactions in a native-like environment.



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