ﻻ يوجد ملخص باللغة العربية
Pain is a multidimensional process, which can be modulated by emotions, however, the mechanisms underlying this modulation are unknown. We used pictures with different emotional valence (negative, positive, neutral) as primes and applied electrical painful stimuli as targets to healthy participants. We assessed pain intensity and unpleasantness ratings and recorded electroencephalograms (EEG). We found that pain unpleasantness, and not pain intensity ratings were modulated by emotion, with increased ratings for negative and decreased for positive pictures. We also found two consecutive gamma band oscillations (GBOs) related to pain processing from time frequency analyses of the EEG signals. An early GBO had a cortical distribution contralateral to the painful stimulus, and its amplitude was positively correlated with intensity and unpleasantness ratings, but not with prime valence. The late GBO had a centroparietal distribution and its amplitude was larger for negative compared to neutral and positive pictures. The emotional modulation effect (negative versus positive) of the late GBO amplitude was positively correlated with pain unpleasantness. The early GBO might reflect the overall pain perception, possibly involving the thalamocortical circuit, while the late GBO might be related to the affective dimension of pain and top-down related processes.
Chronic pain affects about 100 million adults in the US. Despite their great need, neuropharmacology and neurostimulation therapies for chronic pain have been associated with suboptimal efficacy and limited long-term success, as their mechanisms of a
The posterior parietal cortex (PPC) has a unique role in memory retrieval: fMRI and electrocorticography studies suggest that within the ventral PPC (VPC) specifically, there is an anterior-posterior functional divergence between externally-oriented
Paul Bach Y Rita [1] is the precursor of sensory substitutions. He started thirty years ago using visuo-tactile prostheses with the intent of satisfying blind people. These prostheses, called Tactile Vision Substitution Systems (TVSS), transform a se
It has been hypothesized that Gamma cortical oscillations play important roles in numerous cognitive processes and may involve psychiatric conditions including anxiety, schizophrenia, and autism. Gamma rhythms are commonly observed in many brain regi
Oscillations are a hallmark of neural population activity in various brain regions with a spectrum covering a wide range of frequencies. Within this spectrum gamma oscillations have received particular attention due to their ubiquitous nature and to