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A three-dimensional unilateral contact problem for articular cartilage layers attached to subchondral bones shaped as elliptic paraboloids is considered in the framework of the biphasic cartilage model. The main novelty of the study is in accounting not only for the normal (vertical), but also for tangential vertical (horisontal) displacements of the contacting surfaces. Exact general relationships have been established between the contact approach and some integral characteristics of the contact pressure, including the contact force. Asymptotic representations for the contact pressure integral characteristics are obtained in terms of the contact approach and some integral characteristics of the contact zone. The main result is represented by the first-order approximation problem.
We consider a viscoelastic body occupying a smooth bounded domain of $R^3$ under the effects of volumic traction forces. Inertial effects are considered: hence, the equation describing the evolution of displacements is of the second order in time. On
Radiosensitizers can increase the local treatment efficacy under a relatively low and safe radiation dose, thereby facilitating tumor eradication and minimizing side effects. Here, we report a new class of radiosensitizers that contain several gold (
Blood system functions are very diverse and important for most processes in human organism. One of its primary functions is matter transport among different parts of the organism including tissue supplying with oxygen, carbon dioxide excretion, drug
The goal of immunotherapy is to enhance the ability of the immune system to kill cancer cells. Immunotherapy is more effective and, in general, the prognosis is better, when more immune cells infiltrate the tumor. We explore the question of whether t
Despite numerous advances in the field of tissue engineering and regenerative medicine, monitoring the formation of tissue regeneration and its metabolic variations during culture is still a challenge and mostly limited to bulk volumetric assays. Her