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Flattening filter free (FFF) beams due to their non-uniformity, are sub-optimal for larger field sizes. The purpose of this study was to investigate the incident electron beam distributions that would produce flat FFF beams without the use of flattening filter. Monte Carlo (MC) simulations with BEAMnrc and DOSXYZnrc codes have been performed to evaluate the feasibility of this approach. The dose distributions in water for open 6MV beams were simulated using Varian 21EX linac head model, which will be called flattening filter (FF) model. Flattening filter has then been removed from FF model, and MC simulations were performed using (1) 6 MeV electrons incident on the target, (2) 6 MeV electron beam with electron angular distributions optimized to provide as flat dose profiles as possible. Configuration (1) represents FFF beam while configuration (2) allowed producing a flat FFF (F4) beam. Optimizations have also been performed to produce flattest profiles for a set of dose rates (DRs) in the range from 1.25 to 2.4 of the DR of FF beam. Profiles and percentage depth doses PDDs from 6MV F4 beams have been calculated and compared to those from FF beam. Calculated profiles demonstrated improved flatness of the FFF beams. In fact, up to field sizes within the circle of 35 cm diameter the flatness of F4 beam at dmax was better or comparable to that of FF beam. At 20 cm off-axis the dose increased from 52% for FFF to 92% for F4 beam. Also, profiles of F4 beams did not change considerably with depth, and for large fields out-of-field dose was reduced by about a factor of two compared to FF beam. PDDs from F4 beams were similar to those of FFF beam. The DR for the largest modeled (44 cm diameter) F4 beam was higher than the DR from FF beam by a factor of 1.25. It was shown that the DR can be increased while maintaining beam flatness, but at the cost of reduced field size.
Suppressing the effects of scattered radiation in flat panel detector, FPD, based CBCT still remains to be a challenge. To address the scatter problem, we have been investigating the feasibility of a two dimensional antiscatter grid (2D ASG) concept
Purpose: To investigate the validity of two Monte Carlo simulation absolute dosimetry approaches in the case of a small field dedicated `D-shaped collimator used for the retinoblastoma treatment with external photon beam radiotherapy. Methods: The
The diagrammatic Monte Carlo (Diag-MC) method is a numerical technique which samples the entire diagrammatic series of the Greens function in quantum many-body systems. In this work, we incorporate the flat histogram principle in the diagrammatic Mon
Results of a Monte Carlo code intercomparison exercise for simulations of the dose enhancement from a gold nanoparticle (GNP) irradiated by X-rays have been recently reported. To highlight potential differences between codes, the dose enhancement rat
We study the propagation of nucleons and nuclei in tissue-like media within a Monte Carlo Model for Heavy-ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.2). The model takes into account fragmentation of projectile nuclei and secondary int