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Magnetic field fluctuations arising from fundamental spins are ubiquitous in nanoscale biology, and are a rich source of information about the processes that generate them. However, the ability to detect the few spins involved without averaging over large ensembles has remained elusive. Here we demonstrate the detection of gadolinium spin labels in an artificial cell membrane under ambient conditions using a single-spin nanodiamond sensor. Changes in the spin relaxation time of the sensor located in the lipid bilayer were optically detected and found to be sensitive to near-individual proximal gadolinium atomic labels. The detection of such small numbers of spins in a model biological setting, with projected detection times of one second, opens a new pathway for in-situ nanoscale detection of dynamical processes in biology.
Nuclear magnetic resonance (NMR) is a powerful method for determining the structure of molecules and proteins. While conventional NMR requires averaging over large ensembles, recent progress with single-spin quantum sensors has created the prospect o
We propose a method for detecting the presence of a single spin in a crystal by coupling it to a high-quality factor superconducting planar resonator. By confining the microwave field in a constriction of nanometric dimensions, the coupling constant
We experimentally demonstrate a simple and robust protocol for the detection of weak radio-frequency magnetic fields using a single electron spin in diamond. Our method relies on spin locking, where the Rabi frequency of the spin is adjusted to match
The strong driving regime occurs when a quantum two-level system is driven with an external field whose amplitude is greater or equal to the energy splitting between the systems states, and is typically identified with the breaking of the rotating wa
We use micromagnetic simulation to demonstrate layer-selective detection of magnetization directions from magnetic dots having two recording layers by using a spin-torque oscillator (STO) as a read device. This method is based on ferromagnetic resona