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تسجيل مستخدم جديدRecovery of state-specific potential of molecular motor from single-molecule trajectory
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We have developed a novel method to evaluate the potential profile of a molecular motor at each chemical state from only the probes trajectory and applied it to a rotary molecular motor F$_1$-ATPase. By using this method, we could also obtain the information regarding the mechanochemical coupling and energetics. We demonstrate that the position-dependent transition of the chemical states is the key feature for the highly efficient free-energy transduction by F$_1$-ATPase.
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Transport of intracellular cargo is often mediated by teams of molecular motors that function in a chaotic environment and varying conditions. We show that the motors have unique steady state behavior which enables transport modalities that are robus
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This mini review focuses on conductance measurements through molecular junctions containing few tens of molecules, which are fabricated along two approaches: (i) conducting atomic force microscope contacting a self-assembled monolayers on metal surfa
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